About

Sung Min Ma is an Assistant Professor of Clinical Psychiatry and an Attending Psychiatrist on the Consultation-Liaison Service at Pennsylvania Hospital. He serves as the Medical Director of Penn Total Recovery at Penn Presbyterian Medical Center and is a Faculty Champion for the Addiction Psychiatry Certificate Program within the Penn Psychiatry Residency. Dr. Ma completed his undergraduate studies with a BA in Economics at Swarthmore College in 2012 and earned his MD from Tufts University School of Medicine in 2019. His professional focus includes clinical psychiatry with particular involvement in addiction psychiatry and consultation-liaison psychiatry, contributing to patient care and educational initiatives within the University of Pennsylvania's Perelman School of Medicine.

Research topics

• Organic chemistry
• Chemistry
• Computer Science
• Materials science
• Nanotechnology
• Biochemistry
• Crystallography
• Physical chemistry
• Chemical engineering

Selected publications

• A MOF‐based Ultra‐Strong Acetylene Nano‐trap for Highly Efficient C₂H₂/CO₂ Separation

  Angewandte Chemie International Edition · 2021 · 278 citations

  Senior authorCorresponding
  • Crystallography
  • Materials science
  • Chemistry

  .

  DOI

• Metal–Organic Framework Based Hydrogen-Bonding Nanotrap for Efficient Acetylene Storage and Separation

  Journal of the American Chemical Society · 2021 · 340 citations

  Senior authorCorresponding
  • Chemistry
  • Chemical engineering
  • Physical chemistry

  selectivity. This work provides a novel and powerful approach to address the tradeoff of this extremely challenging gas separation.

  DOI

• Fabricating Covalent Organic Framework Capsules with Commodious Microenvironment for Enzymes

  Journal of the American Chemical Society · 2020 · 373 citations

  • Chemistry
  • Nanotechnology
  • Organic chemistry

  Enzyme immobilization has been demonstrated to be a favorable protocol to promote industrialization of biomacromolecules. Despite tremendous efforts to develop new strategies and materials to realize this process, maintaining enzyme activity is still a formidable challenge. Herein we created a sacrificial templating method, using metal-organic frameworks (MOFs) as sacrificial templates to construct hollow covalent organic framework (COF) capsules for enzyme encapsulation. This strategy can provide a capacious microenvironment to unleash enzyme molecules. The improved conformational freedom of enzymes, enhanced mass transfer, and protective effect against the external environment ultimately boosted the enzymatic activities. We also found that this strategy possesses high versatility that is suitable for diverse biomacromolecules, MOF templates, and COF capsules. Moreover, the dimensions, pore sizes, and shell thickness of COF capsules can be conveniently tuned, allowing for customizing bioreactors for specific functions. For example, coencapsulation of different enzymes with synergistic functions were successfully demonstrated using this bioreactor platform. This study not only opens up a new avenue to overcome the present limitations of enzymatic immobilization in porous matrixes but also provides new opportunities for construction of biomicrodevices or artificial organelles based on crystalline porous materials.

  DOI

• Covalent organic frameworks for separation applications

  Chemical Society Reviews · 2020 · 1372 citations

  Senior authorCorresponding
  • Computer Science
  • Nanotechnology
  • Chemistry

  Covalent organic frameworks (COFs) are an emerging class of crystalline porous polymers with highly tuneable structures and functionalities. COFs have been proposed as ideal materials for applications in the energy-intensive field of molecular separation due to their notable intrinsic features such as low density, exceptional stability, high surface area, and readily adjustable pore size and chemical environment. This review attempts to highlight the key advancements made in the synthesis of COFs for diverse separation applications such as water treatment or the separation of gas mixtures and organic molecules, including chiral and isomeric compounds. Methods proposed for the fabrication of COF-based columns and continuous membranes for practical applications are also discussed in detail. Finally, a perspective regarding the remaining challenges and future directions for COF research in the field of separation has also been presented.

  DOI

Recent grants

• CAREER: Development of Mesoporous Metal-Organic Frameworks as a New Type of Platform for Enzyme Immobilization

  NSF · $575k · 2014–2020

• Functional Porous Organic Polymers as Advanced Decontamination Materials for Water Purification

  NSF · $330k · 2017–2021

• Functional Porous Organic Polymers as Advanced Decontamination Materials for Water Purification

  NSF · $150k · 2021–2022

Frequent coauthors

• Hong‐Cai Zhou

  Texas A&M University

  177 shared

• Łukasz Wojtas

  University of South Florida

  166 shared

• Briana Aguila

  147 shared

• Wen‐Yang Gao

  129 shared

• Ayman Nafady

  117 shared

• Abdullah M. Al‐Enizi

  King Saud University

  93 shared

• Daqiang Yuan

  Fujian Institute of Research on the Structure of Matter

  91 shared

• Gaurav Verma

  University of North Texas

  73 shared

Education

• PhD, Chemistry & Biochemistry

  Miami University

  2008

• BS, Chemistry

  Jilin University

  2003

Similar researchers at University of Pennsylvania

• John Q. Trojanowskih-296
• Craig B. Thompsonh-277
• Daniel J Raderh-236
• Carl H. Juneh-218
• M. Celeste Simonh-185