Robert M. Nelson

Global Economic Effects of COVID-19

2020-03-28 · 319 citations

From the Summary: Since the COVID-19 [coronavirus disease 2019] outbreak was first diagnosed, it has spread to over 190 countries and all U S states The pandemic is having a noticeable impact on global economic growth Estimates so far indicate the virus could trim global economic growth by as much as 2 0% per month if current conditions persist and raise the risks of a global economic recession similar in magnitude to that experienced during the Great Depression of the 1930s Global trade could a…

Inclusion of Adolescents in Adult Clinical Trials: Report of the Institute for Advanced Clinical Trials for Children’s Pediatric Innovation Research Forum

Therapeutic Innovation & Regulatory Science · 2021-04-02 · 26 citations

A companion for the festivals and fasts of the Church of England, with collects and prayers for each solemnity

2024-09-10 · 5 citations

Extent of Safety Database in Pediatric Drug Development: Types of Assessment, Analytical Precision, and Pathway for Extrapolation through On-Target Effects

arXiv (Cornell University) · 2022-11-23 · 2 citations

Pediatric patients should have access to medicines that have been appropriately evaluated for safety and efficacy. Given this goal of revised labelling, the adequacy of the pediatric clinical development plan and resulting safety database must inform a favorable benefit-risk assessment for the intended use of the medicinal product. While extrapolation from adults can be used to support efficacy of drugs in children, there may be a reluctance to use the same approach in safety assessments, wiping…

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Elsevier eBooks · 2024-01-01