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Jeffrey Stephen Gerber

Jeffrey Stephen Gerber

University of Pennsylvania · Rehabilitation Medicine

Active 1961–2026

h-index73
Citations19.7k
Papers608254 last 5y
Funding—

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About

Jeffrey Stephen Gerber, M.D., Ph.D., M.S.C.E, is a Professor of Pediatrics (Infectious Diseases) at the Children's Hospital of Philadelphia. He serves as an Attending Physician in the Division of Infectious Diseases at the same hospital and is a Senior Scholar at the Center for Clinical Epidemiology and Biostatistics at the University of Pennsylvania. Dr. Gerber holds the position of Distinguished Chair in the Department of Pediatrics at the Children's Hospital of Philadelphia and is an Associate Chief Clinical Research Officer at the Children's Hospital of Philadelphia Research Institute. He is also the Deputy Director of the Center for Pediatric Clinical Effectiveness at the Children's Hospital of Philadelphia. His research expertise focuses on the epidemiology and outcomes of antimicrobial use, with clinical expertise in antimicrobial stewardship.

Research topics

  • Medicine
  • Microbiology
  • Biochemistry
  • Immunology
  • Virology
  • Environmental health
  • Bioinformatics
  • Pathology
  • Biology
  • Genetics

Selected publications

  • Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios

    JAMA Pediatrics · 2021-01-29 · 298 citations

    articleOpen access

    Importance: Maternally derived antibodies are a key element of neonatal immunity. Understanding the dynamics of maternal antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and subsequent transplacental antibody transfer can inform neonatal management as well as maternal vaccination strategies. Objective: To assess the association between maternal and neonatal SARS-CoV-2-specific antibody concentrations. Design, Setting, and Participants:…

    PublisherOA PDFDOI

  • Bacterial colonization reprograms the neonatal gut metabolome

    Nature Microbiology · 2020 · 126 citations

    DOI

  • Appropriateness of Antibiotic Prescribing in United States Children’s Hospitals: A National Point Prevalence Survey

    Clinical Infectious Diseases · 2020 · 83 citations

    BACKGROUND: Studies estimate that 30%-50% of antibiotics prescribed for hospitalized patients are inappropriate, but pediatric data are limited. Characterization of inappropriate prescribing practices for children is needed to guide pediatric antimicrobial stewardship. METHODS: Cross-sectional analysis of antibiotic prescribing at 32 children's hospitals in the United States. Subjects included hospitalized children with ≥ 1 antibiotic order at 8:00 am on 1 day per calendar quarter, over 6 quarte…

    PublisherOA PDFDOI

  • Antibiotic exposure is associated with minimal gut microbiome perturbations in healthy term infants

    Microbiome · 2025-01-24 · 10 citations

    articleOpen access

    BACKGROUND: The evolving infant gut microbiome influences host immune development and later health outcomes. Early antibiotic exposure could impact microbiome development and contribute to poor outcomes. Here, we use a prospective longitudinal birth cohort of n = 323 healthy term African American children to determine the association between antibiotic exposure and the gut microbiome through shotgun metagenomics sequencing as well as bile acid profiles through liquid chromatography-mass spectrom…

    PublisherOA PDFDOI

  • Disparities in Nirsevimab Uptake Across a Pediatric Primary Care Network

    PEDIATRICS · 2025-07-17 · 6 citations

    articleOpen accessSenior author

    OBJECTIVE: Nirsevimab, a monoclonal antibody for respiratory syncytial virus (RSV) prophylaxis, debuted during the 2023-2024 RSV season. The objective of this study was to examine the distribution of nirsevimab to determine factors associated with nirsevimab receipt. METHODS: Primary care attendee cohort of children younger than 8 months attending 1 of 32 pediatric primary care practices with almost universal nirsevimab availability. Eligible children had at least 1 primary care visit within 14…

    PublisherOA PDFDOI

Frequent coauthors

Labs

  • Gerber LabPI

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