Hongmin Li

· Professor, Pharmacology and Toxicology

University of Arizona · Biochemistry and Molecular Biology

Active 1993–2025

h-index75

Citations20.3k

Papers545141 last 5y

Funding$30.4M

Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.

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About

Hongmin Li is a Professor in the Department of Pharmacology and Toxicology at the University of Arizona. His professional profile is accessible through the university's website, where he is listed as a faculty member within the Biochemistry and Molecular & Cellular Biology Graduate Program. The page does not provide specific details about his research focus, background, or key contributions, but his role indicates a specialization in pharmacology and toxicology within the broader context of biochemistry and molecular biology.

Research topics

Medicine
Virology
Internal medicine
Environmental health
Chemistry
Pharmacology
Biology

Selected publications

The Unique Properties and Click Capacity of the Tetrazine Group Enable Tetrazine Allyl Acetate to Serve as a Versatile Bis-Thiol Bioconjugation and Functionalization Agent
JACS Au · 2025-10-01 · 4 citations
articleOpen access
The inverse electron demand Diels–Alder (IEDDA) click reaction of tetrazine (Tz) with trans-cyclooctene (TCO), which takes place at an exceptionally high rate, has excellent orthogonality and biocompatibility. As a result, the unrivaled capacity of this process enables it to serve as a viable chemical tool for protein modification even in humans. However, the utility of this click reaction is impeded by the limited number of practical methods for the incorporation of the Tz moiety into proteins.…
Publisher DOI
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with 6-((5-(2-(ethyl(methyl)amino)ethyl)-2,3-difluorophenxy)methyl)-4-methylphridin-2-amine
2025-08-21
dataset1st authorCorresponding
Publisher DOI
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with 6-((5-(2-(dimethylamino)ethyl)-2,3-difluorophenoxy)methyl)-4-methylpyridin-2-amine
2025-08-20
dataset1st authorCorresponding
Publisher DOI
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain bound with 6-((2,3-difluoro-5-(2-(piperidin-1-yl)ethyl)phenoxy)methyl)-4-methylpyridin-2-amine
2025-08-20
dataset1st authorCorresponding
Publisher DOI
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain bound with 6-((5-(2-(azetidin-1-yl)ethyl)-2,3-difluorophenxy)methyl)-4-methylpyridin-2-amine
2025-08-20
dataset1st authorCorresponding
Publisher DOI

Recent grants

NIH Grant R56AI074917
NIH · $194k · 2010
High throughput screening of orthosteric inhibitors of flavivirus protease
NIH · $524k · 2017–2018
New Use of Old Drugs for Zika Virus
NIH · $447k · 2017–2021

Frequent coauthors

Zhong Li
237 shared
Laura D. Kramer
New York State Department of Health
83 shared
Roy A. Mariuzza
Institute for Bioscience and Biotechnology Research
77 shared
Nilesh K. Banavali
University at Albany, State University of New York
70 shared
Pei‐Yong Shi
Northeastern University
66 shared
Matthew Brecher
GlaxoSmithKline (United States)
57 shared
Anil Mathew Tharappel
53 shared
Griselda Hernández
Wadsworth Center
50 shared

Education

PhD, Molecular Biology
Institute of Biophysics Chinese Academy of Sciences
1995
M.Sc, Molecular Biology
Institute of Biophysics Chinese Academy of Sciences
1993
B.Sc, Biology
Peking University
1990

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