Brian T. Fisher

University of Pennsylvania · Rehabilitation Medicine

Active 1944–2026

h-index49

Citations13.6k

Papers472156 last 5y

Funding$692k

Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.

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About

Brian T. Fisher, DO, MSCE, MPH, is a Professor of Pediatrics (Infectious Diseases) at the Children's Hospital of Philadelphia. He is also a Senior Scholar at the Center for Clinical Epidemiology and Biostatistics at the University of Pennsylvania and serves as the Director of Infectious Diseases and Oncology Clinical Care at the Children's Hospital of Philadelphia. His research focuses on infectious diseases, epidemiology, and biostatistics, contributing to clinical epidemiology and pediatric infectious disease care.

Research topics

Medicine
Internal medicine
Intensive care medicine
Pathology
Surgery
Immunology
Environmental health
Dermatology
Clinical psychology
Psychology

Selected publications

Guideline for the Management of Fever and Neutropenia in Pediatric Patients With Cancer and Hematopoietic Cell Transplantation Recipients: 2023 Update
Journal of Clinical Oncology · 2023 · 169 citations
PURPOSE: To update a clinical practice guideline (CPG) for the empiric management of fever and neutropenia (FN) in pediatric patients with cancer and hematopoietic cell transplantation recipients. METHODS: The International Pediatric Fever and Neutropenia Guideline Panel reconvened to conduct the second update of this CPG. We updated the previous systematic review to identify new randomized controlled trials (RCTs) evaluating any strategy for the management of FN in pediatric patients. Using the…
DOI
Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children’s Oncology Group
Haematologica · 2020 · 168 citations
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DOI
Association of Social Distancing, Population Density, and Temperature With the Instantaneous Reproduction Number of SARS-CoV-2 in Counties Across the United States
JAMA Network Open · 2020-07-23 · 154 citations
articleOpen access
Importance: Local variation in the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across the United States has not been well studied. Objective: To examine the association of county-level factors with variation in the SARS-CoV-2 reproduction number over time. Design, Setting, and Participants: This cohort study included 211 counties, representing state capitals and cities with at least 100 000 residents and including 178 892 208 US residents, in 46 states and the Di…
Publisher OA PDF DOI
Clinical Practice Guideline for Systemic Antifungal Prophylaxis in Pediatric Patients With Cancer and Hematopoietic Stem-Cell Transplantation Recipients
Journal of Clinical Oncology · 2020 · 138 citations
PURPOSE: To develop a clinical practice guideline for systemic antifungal prophylaxis in pediatric patients with cancer and hematopoietic stem-cell transplantation (HSCT) recipients. METHODS: Recommendations were developed by an international multidisciplinary panel that included a patient advocate. We conducted a systematic review of systemic antifungal prophylaxis in children and adults with cancer and HSCT recipients. The Grading of Recommendations Assessment, Development, and Evaluation appr…
DOI
Safety, outcomes, and pharmacokinetics of isavuconazole as a treatment for invasive fungal diseases in pediatric patients: a non-comparative phase 2 trial
Antimicrobial Agents and Chemotherapy · 2024-11-14 · 19 citations
articleOpen access
Invasive aspergillosis (IA) and mucormycosis (IM) cause significant morbidity and mortality in immunocompromised and/or hospitalized patients. Isavuconazonium sulfate, a prodrug of the antifungal triazole isavuconazole, has been approved for treatment of IA and IM in adults; and was recently approved in children. This study describes the outcomes, safety, and pharmacokinetics of isavuconazole for the treatment of proven, probable, or possible IA or IM in children. In this phase 2, open-label, no…
Publisher DOI

Recent grants

Fungal biomarkers for diagnosis and response to therapy for pediatric candidemia
NIH · $692k · 2014–2019

Frequent coauthors

Richard Aplenc
Hospital for Sick Children
360 shared
Lillian Sung
Hospital for Sick Children
293 shared
Yimei Li
Children's Hospital of Philadelphia
249 shared
Alix E. Seif
Children's Hospital of Philadelphia
248 shared
L. Lee Dupuis
University of Toronto
230 shared
Elio Castagnola
Istituto Giannina Gaslini
223 shared
Bob Phillips
Hull York Medical School
222 shared
Thomas Lehrnbecher
Goethe University Frankfurt
211 shared

Labs

Fisher LabPI

Education

Master of Science in Clinical Epidemiology, Biostatistics, Epidemiology and Informatics
University of Pennsylvania
2009
DO, Chicago College of Osteopathic Medicine
Midwestern University
2002
Master of Public Health, Epidemiology
University of Illinois at Chicago
1998
Bachelor of Science, Biology
University of Notre Dame
1995

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