Xiaotong Li

About

Xiaotong Li is an assistant professor in the Department of Chemistry at North Carolina State University, having joined the faculty in January 2024. She obtained her B.S. in chemistry from Nankai University in Tianjin, China, in 2016, and earned her Ph.D. in chemistry from Northwestern University in 2021 under the supervision of Prof. Mercouri Kanatzidis. Her doctoral research focused on structure-property relationships of 2D halide perovskites. Following her Ph.D., she conducted postdoctoral research at the California Institute of Technology with Prof. Kimberly See, working on cathode materials for Li and Na-ion batteries. Her research group primarily focuses on the synthesis and structural determination of new hybrid and inorganic materials for energy-related applications. She is particularly interested in designing new halide perovskites and hybrid organic-inorganic metal halides, as well as studying their structure-property relationships.

Research topics

• Medicine
• Biology
• Computational biology
• Materials science
• Computer Science
• Composite material
• Genetics
• Evolutionary biology
• Ecology
• Cell biology

Selected publications

• A multimodal cell census and atlas of the mammalian primary motor cortex

  Nature · 2021 · 564 citations

  . First, our study reveals a unified molecular genetic landscape of cortical cell types that integrates their transcriptome, open chromatin and DNA methylation maps. Second, cross-species analysis achieves a consensus taxonomy of transcriptomic types and their hierarchical organization that is conserved from mouse to marmoset and human. Third, in situ single-cell transcriptomics provides a spatially resolved cell-type atlas of the motor cortex. Fourth, cross-modal analysis provides compelling ev…

  DOI

• An Efficient Stevia rebaudiana Transformation System and In vitro Enzyme Assays Reveal Novel Insights into UGT76G1 Function

  Scientific Reports · 2020 · 20 citations

  Stevia rebaudiana (Bertoni) is one of a very few plant species that produce zero calorie, sweet compounds known as steviol glycosides (SG). SGs differ in their sweetness and organoleptic properties depending on the number and positioning of sugar groups on the core steviol backbone. There is great interest of modulating the SG profiles of the Stevia plant to enhance the flavor profile for a given application in the food and beverage industries. Here, we report a highly efficient Agrobacterium-me…

  PublisherOA PDFDOI

• Comparative Phylogenomic Analysis Reveals Evolutionary Genomic Changes and Novel Toxin Families in Endophytic <i>Liberibacter</i> Pathogens

  Microbiology Spectrum · 2021 · 9 citations

  pathogens and will facilitate the development of new detection and blockage methods targeting the toxins.

  PublisherDOI

• The <i>CYP71A</i> , <i>NIT</i> , <i>AMI</i> , and <i>IAMH</i> gene families are dispensable for indole-3-acetaldoxime-mediated auxin biosynthesis in <i>Arabidopsis</i>

  The Plant Cell · 2025-10-15 · 4 citations

  articleOpen access

  The auxin indole-3-acetic acid (IAA) governs plant development and environmental responses. Although the indole-3-pyruvic acid (IPyA) pathway is the predominant route for IAA biosynthesis, other pathways have been proposed, such as the indole-3-acetaldoxime (IAOx) pathway. The IAOx pathway has garnered attention due to its supposed activation in auxin-overproducing mutants (e.g. sur1, sur2, ugt74b1) and the auxin-like responses triggered by exogenous application of its proposed intermediates IAO…

  PublisherDOI

• Multi-Omics analyses reveal dynamic interactions between DNA methylation and transcriptional regulation during black raspberry ripening

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-27

  preprintOpen access

  Abstract We profiled developmental-series transcriptome, methylome, and metabolome profiling to reveal extensive epigenetic reprogramming during black raspberry ( Rubus occidentalis ) fruit ripening. Fruit tissues exhibit globally higher DNA methylation than leaves, particularly in CHG and CHH contexts. Local methylation in all cytosine contexts progressively decreases in promoter regions during ripening, whereas CHG and CHH methylation increase in transposon-rich regions. Two primary methylatio…

  PublisherOA PDFDOI

Frequent coauthors

• Zhenhua Zhang

  Fudan University

  40 shared

• Longhua Fan

  Zhongshan Hospital

  32 shared

• Clint Chapple

  Purdue University West Lafayette

  21 shared

• Feiyu Kang

  Tsinghua University

  18 shared

• Jing Liu

  Central South University

  17 shared

• Ying Xia

  Edith Cowan University

  17 shared

• Jianjun Liu

  Zhongshan Hospital

  16 shared

• Yafei Zhang

  Yantaishan Hospital

  16 shared

Labs

• Xiaotong Li LabPI

Similar researchers at North Carolina State University

• Jonathan Lindseyh-101
• Phil Castellanoh-86
• Masahiko Taniguchih-73