Timothy J. Kamp
· Professor - Medicine; Co-director - Stem Cell and Regenerative Medicine CenterUniversity of Wisconsin-Madison · Anatomy
Active 1985–2026
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About
Timothy J. Kamp is a Professor in Medicine and Co-director of the Stem Cell and Regenerative Medicine Center at the University of Wisconsin–Madison. His research interests focus on cardiogenesis from embryonic stem cells, exploring the processes involved in heart development and regeneration. His work contributes to understanding how stem cells can be directed to form cardiac tissue, which has implications for regenerative medicine and treatment of heart diseases.
Research topics
- Medicine
- Internal medicine
- Genetics
- Biology
- Cardiology
- Bioinformatics
- Cell biology
- Pharmacology
- Endocrinology
- Intensive care medicine
Selected publications
Proceedings of the National Academy of Sciences · 2020 · 107 citations
= 16). We observed a complex landscape of sarcomeric proteoforms arising from combinatorial PTMs, alternative splicing, and genetic variation in HCM. A coordinated decrease of phosphorylation in important myofilament and Z-disk proteins with a linear correlation suggests PTM cross-talk in the sarcomere and dysregulation of protein kinase A pathways in HCM. Strikingly, we discovered that the sarcomeric proteoform alterations in the myocardium of HCM patients undergoing septal myectomy were remark…
Basic and Translational Research in Cardiac Repair and Regeneration
Journal of the American College of Cardiology · 2021 · 105 citations
This paper aims to provide an important update on the recent preclinical and clinical trials using cell therapy strategies and engineered heart tissues for the treatment of postinfarction left ventricular remodeling and heart failure. In addition to the authors' own works and opinions on the roadblocks of the field, they discuss novel approaches for cardiac remuscularization via the activation of proliferative mechanisms in resident cardiomyocytes or direct reprogramming of somatic cells into ca…
Journal of the American College of Cardiology · 2020 · 57 citations
Circulation Arrhythmia and Electrophysiology · 2021 · 33 citations
Senior authorCorresponding[Figure: see text].
Frontiers in Bioengineering and Biotechnology · 2025-05-23 · 8 citations
articleOpen accessIntroduction: Cardiac fibroblasts deposit and turnover the extracellular matrix in the heart, as well as secrete soluble factors that play critical roles in development, homeostasis, and disease. Coculture of CFs and human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (CMs) enhances CM mechanical output, yet the mechanism remains unclear. Methods: engineered platform to compare the effects on CM mechanical function of direct CM-CF Coculture and soluble signaling alone through CF C…
Recent grants
NIH · $61.8M · 2013
NIH · $652k · 2006
NIH · $221k · 2001
Frequent coauthors
- 106 shared
James A. Thomson
Morgridge Institute for Research
- 74 shared
Jianhua Zhang
- 71 shared
Amanda M. Herman
Chapman University
- 67 shared
José Jalife
Spanish National Centre for Cardiovascular Research
- 66 shared
Todd J. Herron
University of Michigan–Ann Arbor
- 65 shared
Sean P. Palecek
University of Wisconsin–Madison
- 61 shared
Matthew Klos
Case Western Reserve University
- 61 shared
Luqia Hou
Merck & Co., Inc., Rahway, NJ, USA (United States)
Education
- 1995
Ph.D., Cardiogenesis
University of Wisconsin-Madison
- 1991
M.S., Cardiogenesis
University of Wisconsin-Madison
- 1988
B.S., Biology
University of Wisconsin-Madison
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