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Sayan Bhattacharya

Sayan Bhattacharya

· Assistant Professor

University of Maryland, College Park · The Harriet Tubman Department of Women, Gender, and Sexuality Studies

Active 1991–2024

h-index24
Citations2.0k
Papers9541 last 5y
Funding
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About

Sayan Bhattacharya is an Assistant Professor in the Harriet Tubman Department of Women, Gender, and Sexuality Studies at the University of Maryland. They earned their doctorate in Feminist Studies from the University of Minnesota. Their research focuses on ethnographic and archival explorations of Indian trans communities, examining strategies they deploy to navigate environments saturated by violence. Their work explores gestures of pleasure, negotiations with the state, care labor, and dark humor as means for trans communities to endure and refuse violence. Bhattacharya's scholarship stages conversations between anthropologies of everyday life, trans, queer, and critical disability studies, as well as anti-caste literatures, to study efforts to reproduce inhabitable everyday spaces. Their research has been published in various academic journals including Radical History Review, Global Public Health, Transgender Studies Quarterly, and others. They received the 2023 Sylvia Rivera Award in Transgender Studies for their essay on transgender life-making during the pandemic. Additionally, Bhattacharya volunteers with community-led trans and disability rights organizations in West Bengal, India.

Research topics

  • Internal medicine
  • Cancer research
  • Oncology
  • Immunology
  • Cell biology
  • Biochemistry
  • Medicine
  • Biology

Selected publications

  • Advances in Glioblastoma Therapy: An Update on Current Approaches

    Brain Sciences · 2023 · 193 citations

    Senior authorCorresponding
    • Medicine
    • Oncology
    • Immunology

    Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high grade of malignancy and an extremely unfavorable prognosis. The current efficacy of established treatments for GBM is insufficient, necessitating the prompt development of novel therapeutic approaches. The progress made in the fundamental scientific understanding of GBM is swiftly translated into more advanced stages of therapeutic studies. Despite extensive efforts to identify new therapeutic approaches, GBM exhibits a high mortality rate. The current efficacy of treatments for GBM patients is insufficient due to factors such as tumor heterogeneity, the blood-brain barrier, glioma stem cells, drug efflux pumps, and DNA damage repair mechanisms. Considering this, pharmacological cocktail therapy has demonstrated a growing efficacy in addressing these challenges. Towards this, various forms of immunotherapy, including the immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy have emerged as potential strategies for enhancing the prognosis of GBM. Current investigations are focused on exploring combination therapies to mitigate undesirable side effects and enhance immune responses against tumors. Furthermore, clinical trials are underway to evaluate the efficacy of several strategies to circumvent the blood-brain barrier (BBB) to achieve targeted delivery in patients suffering from recurrent GBM. In this review, we have described the biological and molecular targets for GBM therapy, pharmacologic therapy status, prominent resistance mechanisms, and new treatment approaches. We also discuss these promising therapeutic approaches to assess prospective innovative therapeutic agents and evaluated the present state of preclinical and clinical studies in GBM treatment. Overall, this review attempts to provide comprehensive information on the current status of GBM therapy.

  • Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid-Derived Exosomes

    Pharmaceutical Research · 2022 · 41 citations

    • Cell biology
    • Biology
    • Biochemistry

Frequent coauthors

  • Debabrata Mukhopadhyay

    Nemours Children's Clinic

    64 shared
  • Enfeng Wang

    Nemours Children's Clinic

    42 shared
  • Tanmay Kulkarni

    Mayo Clinic in Florida

    41 shared
  • Ramcharan Singh Angom

    Jacksonville College

    31 shared
  • Shamit K. Dutta

    Jacksonville College

    31 shared
  • Krishnendu Pal

    Mayo Clinic in Florida

    24 shared
  • T. Venkatesan

    University of Oklahoma

    21 shared
  • X. X. Xi

    Lanzhou University

    15 shared

Education

  • Ph.D., Feminist Studies

    University of Minnesota

Awards & honors

  • 2023 Sylvia Rivera Award in Transgender Studies

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