About

Rowan Dorin is an associate professor of history at Stanford University, where he also serves as the director of the Center for Medieval and Early Modern Studies, the director of Honors & Research, and is a core faculty member of the Taube Center for Jewish Studies. He specializes in the history of western Europe and the Mediterranean during the high and late Middle Ages. His research primarily focuses on the interaction between law and society, especially where legal norms conflict with social practices. Additionally, he explores the history of economic life and economic thought, with particular attention to medieval debates over usury and moneylending, as well as the circulation of goods, people, and ideas in the medieval Mediterranean.

Research topics

• Medicine
• Endocrinology
• Internal medicine
• Gastroenterology

Selected publications

• Decreased maximal cortisol secretion rate in patients with cirrhosis: Relation to disease severity

  JHEP Reports · 2021 · 9 citations

  Senior authorCorresponding
  • Internal medicine
  • Endocrinology
  • Medicine

  BACKGROUND & AIMS: Hepatic enzymes play a major role in the metabolic elimination of cortisol, and reduced rates of cortisol clearance have been consistently observed in patients with chronic liver disease. It is less clear whether there are concomitant abnormalities of adrenocortical function in patients with cirrhosis. In the present study, we sought to assess adrenocortical function in patients with cirrhosis using measures of free cortisol appearance and elimination rates that are independent of serum concentrations of cortisol binding proteins. METHODS: analysis used computer-assisted numerical and modelling methods with serial total and free cortisol concentration data to obtain rates of free cortisol appearance and elimination. Rate parameters were obtained in 114 patients with chronic liver disease, including Child-Pugh (CP) ≤8 (n = 53) and CP >8 (n = 61). RESULTS: <0.001) was observed. CONCLUSIONS: estimates were independent of cortisol-binding protein concentrations. Results provide additional evidence of subnormal adrenocortical function in patients with cirrhosis. LAY SUMMARY: We applied numerical analytic methods to characterise adrenocortical function in patients with varying stages of chronic liver disease. We found that patients with more severe cirrhosis have decreased rate of free cortisol elimination and decreased maximal cortisol secretion rate, which is a measure of adrenocortical function. In contrast to conventional measures of adrenocortical function, those obtained using numerical methods were not affected by variation in corticosteroid binding globulin and albumin concentrations. We conclude that patients with cirrhosis demonstrate measurable abnormalities of adrenocortical function, evidence of which supports aspects of the hepatoadrenal syndrome hypothesis.

  DOI

• Dialysis-associated hyperglycemia: manifestations and treatment

  International Urology and Nephrology · 2020 · 17 citations

  • Medicine
  • Internal medicine
  • Endocrinology
  DOI

Recent grants

• NIH Grant M01RR000997

  NIH · $14.4M · 2010

• NIH Grant F32AM007407

  NIH · $29k

• NIH Grant F32DK007407

  NIH · $65k

Frequent coauthors

• Clifford Qualls

  University of New Mexico

  62 shared

• Lawrence M. Crapo

  Stanford University

  21 shared

• Vallabh O. Shah

  16 shared

• Lina Aguirre

  New Mexico VA Health Care System

  14 shared

• Frank K. Urban

  Florida International University

  14 shared

• Andrew R. Hoffman

  Stanford University

  14 shared

• James Eberwine

  University of Pennsylvania

  13 shared

• Antonios H. Tzamaloukas

  Raymond G. Murphy VA Medical Center

  13 shared

Labs

• Vice Provost for Student AffairsPI

Awards & honors

• John Nicholas Brown Prize from the Medieval Academy of Ameri…
• Salo Baron Prize from the American Academy for Jewish Resear…
• Wallace K. Ferguson Prize from the Canadian Historical Assoc…
• Margaret Wade Labarge Prize from the Canadian Society of Med…
• American Historical Association Pacific Coast Branch Book Aw…

Similar researchers at Stanford University

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• Zhenan Baoh-224
• Karl Deisserothh-218
• Michael Snyderh-215
• Roger Blandfordh-205