Luke Borst

About

Sarah Ho is the CVM Director of Student Engagement at the College of Veterinary Medicine at NC State University. Her role involves fostering student success and engagement within the college community. The page emphasizes her position in supporting students' academic and personal growth, but does not provide specific details about her research focus, background, or key contributions.

Research topics

• Medicine
• Biology
• Cell biology
• Pathology
• Cancer research
• Immunology
• Veterinary medicine
• Internal medicine
• Microbiology
• Animal science

Selected publications

• The role of <i>Enterococcus faecalis</i> during co-infection with avian pathogenic <i>Escherichia coli</i> in avian colibacillosis

  Avian Pathology · 2020 · 22 citations

  Senior authorCorresponding

  (EF) enhances survival of APEC in iron restricted conditions. EF co-infection increases APEC virulence in broiler embryos.

  DOI

• A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation

  Frontiers in Oncology · 2021 · 19 citations

  ) as consistently upregulated and central to the ECM gene regulatory network (p < 0.05). Versican expression is prognostic for a poorer metastasis-free and overall survival in patients with osteosarcoma. Together, our results provide a novel experimental framework to study discrete steps in the metastatic process. Using this system, we identify the versican/ECM network dysregulation as a potential contributor to osteosarcoma circulating tumor cell metastasis.

  DOI

• Personalized‐induced neural stem cell therapy: Generation, transplant, and safety in a large animal model

  Bioengineering & Translational Medicine · 2020 · 16 citations

  In this study, we take an important step toward clinical translation by generating the first canine-induced neural stem cells (iNSCs). We explore key aspects of scale-up, persistence, and safety of personalized iNSC therapy in autologous canine surgery models. iNSCs are a promising new approach to treat aggressive cancers of the brain, including the deadly glioblastoma. Created by direct transdifferentiation of fibroblasts, iNSCs are known to migrate through the brain, track down invasive cancer…

  DOI

• Development and Application of Optimized Isolation Methods and Diagnostic PCR Protocols for the Detection of Pathogenic Enterococcus cecorum Isolated from Broiler Chickens

  Avian Diseases · 2025-02-13 · 3 citations

  articleOpen accessSenior author

  Desarrollo y aplicación de métodos de aislamiento optimizados y protocolos de PCR de diagnóstico para la detección de Enterococcus cecorum patógeno aislado de pollos de engorde. Enterococcus cecorum (EC) es un comensal entérico dominante en pollos de engorde. Sin embargo, las cepas patógenas de E. cecorum causan un aumento de la morbilidad y la mortalidad por enfermedad septicémica en la producción de pollos de engorde en todo el mundo. Las infecciones por E. cecorum pueden presentarse como peri…

  PublisherOA PDFDOI

• Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma

  UNC Libraries · 2024-08-27 · 2 citations

  articleOpen access

  Follicular lymphomas (FLs) typically exhibit a chromosome translocation that induces constitutive expression of the anti-apoptotic bcl2 protein and accumulation of additional molecular defects. This rearrangement offers a promising therapeutic target, but its nature as a fundamental driver of FL pathogenesis remains unclear as 15% of cases lack the translocation. We performed an integrated immunohistochemical and genomic investigation of 10 naturally occurring FL cases from domestic dogs, showin…

  PublisherDOI

Frequent coauthors

• Matthew Breen

  Cancer Genetics (United States)

  83 shared

• Rachael Thomas

  North Carolina State University

  74 shared

• Alison A. Motsinger‐Reif

  National Institute of Environmental Health Sciences

  66 shared

• Steven E. Suter

  North Carolina State University

  64 shared

• Dahlia M. Nielsen

  North Carolina State University

  60 shared

• Charles M. Perou

  UNC Lineberger Comprehensive Cancer Center

  60 shared

• Yuri Fedoriw

  University of North Carolina at Chapel Hill

  60 shared

• George W. Small

  University of North Carolina at Chapel Hill

  60 shared

Education

• PhD, Pathobiology

  University of Illinois System

  2009

• DVM

  University of Illinois System

  2005

Similar researchers at North Carolina State University

• Siddhartha Thakurh-36
• Casey Therioth-35
• Isabel Gimenoh-33