Kristin Artinger

About

Eric Schiffman, DDS, MS, is a Professor and the Director of Clinical Research in the School of Dentistry at the University of Minnesota. He has received over $19 million in research funding from the National Institutes of Health (NIH) and has authored over 60 peer-reviewed publications, 12 book chapters, and holds 3 patents with another pending. His past research as an NIH study principal investigator includes developing and publishing validated Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for the most common TMD, applicable in both clinical and research settings. He has also conducted research on TMD management, assessing the long-term effectiveness of medical management versus comprehensive rehabilitation with and without TMJ surgery, and the longitudinal impact of intra-articular TMJ disorders on jaw pain, function, and disability. Additionally, he contributed to the NIH-funded National Dental Practice-Based Research Network by evaluating how dentists manage TMD patients in their practices. His recent work includes developing and clinically testing a new version of the Restful Jaw device, designed to support the jaw during dental procedures, including third molar removal, funded through NIH/NIDCR’s STTR and SBIR grants.

Research topics

• Genetics
• Cell biology
• Biology
• Computational biology
• Computer Science
• Medicine
• Anatomy

Selected publications

• Epigenetic regulation of craniofacial development and disease

  Birth Defects Research · 2023-11-14 · 17 citations

  reviewOpen accessSenior author

  BACKGROUND: The formation of the craniofacial complex relies on proper neural crest development. The gene regulatory networks (GRNs) and signaling pathways orchestrating this process have been extensively studied. These GRNs and signaling cascades are tightly regulated as alterations to any stage of neural crest development can lead to common congenital birth defects, including multiple syndromes affecting facial morphology as well as nonsyndromic facial defects, such as cleft lip with or withou…

  PublisherOA PDFDOI

• Mutations in <i>cdon</i> and <i>boc</i> affect trunk neural crest cell migration and slow-twitch muscle development in zebrafish

  Development · 2023-06-30 · 8 citations

  articleOpen accessSenior author

  The transmembrane proteins cdon and boc are implicated in regulating hedgehog signaling during vertebrate development. Recent work showing roles for these genes in axon guidance and neural crest cell migration suggest that cdon and boc may play additional functions in regulating directed cell movements. We use newly generated and existing mutants to investigate a role for cdon and boc in zebrafish neural crest cell migration. We find that single mutant embryos exhibit normal neural crest phenoty…

  PublisherOA PDFDOI

• Myogenesis gone awry: the role of developmental pathways in rhabdomyosarcoma

  Frontiers in Cell and Developmental Biology · 2025-01-20 · 4 citations

  reviewOpen access

  Rhabdomyosarcoma is a soft-tissue sarcoma that occurs most frequently in pediatric patients and has poor survival rates in patients with recurrent or metastatic disease. There are two major sub-types of RMS: fusion-positive (FP-RMS) and fusion-negative (FN-RMS); with FP-RMS typically containing chromosomal translocations between the PAX3/7-FOXO1 loci. Regardless of subtype, RMS resembles embryonic skeletal muscle as it expresses the myogenic regulatory factors (MRFs), MYOD1 and MYOG. During norm…

  PublisherOA PDFDOI

• Human split hand/foot variants are not as functional as wildtype human <i>PRDM1</i> in the rescue of craniofacial defects

  Birth Defects Research · 2024-03-01 · 2 citations

  articleOpen accessSenior authorCorresponding

  Abstract Background Split hand/foot malformation (SHFM) is a congenital limb disorder presenting with limb anomalies, such as missing, hypoplastic, or fused digits, and often craniofacial defects, including a cleft lip/palate, microdontia, micrognathia, or maxillary hypoplasia. We previously identified three novel variants in the transcription factor, PRDM1 , that are associated with SHFM phenotypes. One individual also presented with a high arch palate. Studies in vertebrates indicate that PRDM…

  PublisherOA PDFDOI

• PRDM paralogs are required for Meckel's cartilage formation during mandibular bone development

  Developmental Biology · 2025-12-04 · 1 citations

  articleOpen access
  PublisherOA PDFDOI

Recent grants

• NIH Grant R01DE017699

  NIH · $1.8M · 2014

• NIH Grant F32HD008209

  NIH · $94k

• NIH Grant U01DE020076

  NIH · $1.9M · 2015

Frequent coauthors

• Brittany T. Truong

  University of Colorado Anschutz Medical Campus

  28 shared

• Linda Roberts

  24 shared

• Anne H. Monsoro-Burq

  Université Paris-Saclay

  22 shared

• James C. Costello

  University of Colorado Cancer Center

  22 shared

• Lomeli C. Shull

  University of Colorado Anschutz Medical Campus

  22 shared

• Laura Hernandez‐Lagunas

  University of Colorado Anschutz Medical Campus

  20 shared

• Heide L. Ford

  University of Colorado Anschutz Medical Campus

  19 shared

• Ezra Lencer

  Lafayette College

  18 shared

Similar researchers at University of Minnesota

• David Bereiterh-56
• Massimo Costalongah-19
• Mansur Ahmadh-16