Karen Bracha Zur
University of Pennsylvania · Rehabilitation Medicine
Active 1994–2026
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About
Karen Bracha Zur, MD, is a Professor of Otorhinolaryngology: Head and Neck Surgery at the Children's Hospital of Philadelphia. She holds the E. Mortimer Newlin Endowed Chair in Pediatric Otolaryngology and Human Communication and the William Potsic Endowed Chair in Pediatric Otolaryngology and Childhood Communication at the same institution. Her clinical expertise includes management of pediatric voice disorders, pediatric airway reconstruction, laryngotracheal reconstruction, pediatric swallowing disorders, and management of larygotracheal papillomatosis. Her research focuses on pediatric voice disorders, laryngotracheal reconstruction, and general pediatric otolaryngology, with specific interests in pediatric airway management and communication. Dr. Zur is actively involved in clinical care and research aimed at improving outcomes for children with complex ENT conditions.
Research topics
- Medicine
- Intensive care medicine
- Surgery
- Internal medicine
- Medical physics
- Anatomy
- Emergency medicine
- Anesthesia
- Pediatrics
Selected publications
International Journal of Pediatric Otorhinolaryngology · 2020-08-04 · 64 citations
articleHuman T follicular helper clones seed the germinal center–resident regulatory pool
Science Immunology · 2023-04-07 · 59 citations
articleOpen accessThe mechanisms by which FOXP3 + T follicular regulatory (Tfr) cells simultaneously steer antibody formation toward microbe or vaccine recognition and away from self-reactivity remain incompletely understood. To explore underappreciated heterogeneity in human Tfr cell development, function, and localization, we used paired TCRVA / TCRVB sequencing to distinguish tonsillar Tfr cells that are clonally related to natural regulatory T cells (nTfr) from those likely induced from T follicular helper (T…
Systemic Bevacizumab for Treatment of Respiratory Papillomatosis: International Consensus Statement
The Laryngoscope · 2021 · 44 citations
OBJECTIVES/HYPOTHESIS: The purpose of this study is to develop consensus on key points that would support the use of systemic bevacizumab for the treatment of recurrent respiratory papillomatosis (RRP), and to provide preliminary guidance surrounding the use of this treatment modality. STUDY DESIGN: Delphi method-based survey series. METHODS: A multidisciplinary, multi-institutional panel of physicians with experience using systemic bevacizumab for the treatment of RRP was established. The Delph…
The Laryngoscope · 2022-01-19 · 23 citations
articleSenior authorCorrespondingOBJECTIVES/HYPOTHESIS: Systemic bevacizumab is a new adjuvant therapy for recurrent respiratory papillomatosis (RRP) that has shown promising preliminary results in children. The objective of this study was to report the largest series to date that includes long-term follow-up data on bevacizumab treatment. STUDY DESIGN: Retrospective chart review. METHODS: Retrospective review of seven pediatric patients treated within the past 6 years with systemic bevacizumab for RRP refractory to traditional…
The Laryngoscope · 2022-05-11 · 20 citations
articleOpen accessRecurrent respiratory papillomatosis (RRP) is a potentially lethal disease caused by the human papillomavirus (HPV) and characterized by recurrent papillomas in the aerodigestive tract. Cases of RRP are expected to be significantly reduced with increased acceptance of the HPV-9 vaccine. Currently, the mainstay of RRP treatment is via surgical intervention, with a minority of patients requiring adjuvant medical therapies during their disease. Several adjuvant therapies have been administered, wit…
Frequent coauthors
- 37 shared
Ian N. Jacobs
Children's Hospital of Philadelphia
- 30 shared
Karthik Balakrishnan
Stanford Health Care
- 26 shared
Catherine K. Hart
Cincinnati Children's Hospital Medical Center
- 25 shared
Luv Javia
University of Pennsylvania
- 24 shared
Michael J. Rutter
University of Cincinnati
- 24 shared
Stephen R. Chorney
Children's Medical Center
- 23 shared
Douglas R. Sidell
Stanford University
- 23 shared
Diego Preciado
Children's National
Education
BS
Yale University
- 1998
MD
Albert Einstein College of Medicine
Awards & honors
- E. Mortimer Newlin Endowed Chair in Pediatric Otolaryngology…
- William Potsic Endowed Chair in Pediatric Otolaryngology and…
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