Joyce C. Chang
University of Pennsylvania · Rehabilitation Medicine
Active 1983–2026
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About
Joyce C. Chang, MD, MSCE, is an Adjunct Assistant Professor of Pediatrics (Rheumatology) at the Perelman School of Medicine at the University of Pennsylvania. She is affiliated with Boston Children's Hospital. Her educational background includes an AB in Biochemical Sciences from Harvard College obtained in 2008, an MD from the University of Pennsylvania, Perelman School of Medicine, earned in 2012, and a Master of Science in Clinical Epidemiology (MSCE) from the same institution completed in 2018. Her research and clinical interests focus on pediatric rheumatology, autoimmune diseases, and the application of clinical epidemiology to improve outcomes in pediatric patients with systemic autoimmune conditions. She has contributed to studies on eosinophilia, lung disease in systemic juvenile idiopathic arthritis, multisystem inflammatory syndrome in children due to COVID-19, and pediatric lupus, among others.
Research topics
- Internal medicine
- Medicine
- Pediatrics
Selected publications
Multisystem Inflammatory Syndrome in Children During the Coronavirus 2019 Pandemic: A Case Series
Journal of the Pediatric Infectious Diseases Society · 2020-05-25 · 390 citations
articleOpen accessWe present a series of 6 critically ill children with multisystem inflammatory syndrome in children. Key findings of this syndrome include fever, diarrhea, shock, and variable presence of rash, conjunctivitis, extremity edema, and mucous membrane changes.
Real-world application of the pediatric Glucocorticoid Toxicity Index in childhood-onset lupus
Seminars in Arthritis and Rheumatism · 2024-07-15 · 3 citations
articleOpen accessSenior authorCorrespondingLupus · 2025-05-20 · 2 citations
articleOpen access1st authorCorrespondingObjectives To assess the potential of a multi-institutional pediatric learning health system for comparative effectiveness research in pediatric-onset systemic lupus erythematosus (SLE), we characterized renin angiotensin aldosterone system (RAAS) inhibitor utilization and the feasibility of ascertaining key treatment indications and outcomes, including hypertension and proteinuria. Methods We identified children with SLE and lupus nephritis (LN) at 6 PEDSnet institutions using previously develo…
A Qualitative Exploration of Adherence to Methotrexate in Juvenile Idiopathic Arthritis
The Journal of Pediatrics · 2025-08-29 · 1 citations
articleOpen accessArthritis Care & Research · 2024-09-23 · 1 citations
articleOpen accessOBJECTIVE: We linked pharmacy dispensing data to clinical data in the electronic health record (EHR) to (1) identify characteristics associated with adherence to methotrexate (MTX) and (2) determine the association between adherence and disease activity in patients with juvenile idiopathic arthritis (JIA). METHODS: We conducted a single-center retrospective cohort study of incident MTX recipients with JIA treated between January 2016 and September 2023 for ≥12 months. Using pharmacy dispensing d…
Recent grants
Frequent coauthors
- 136 shared
Andrea Knight
University of Toronto
- 112 shared
Pamela F. Weiss
Children's Hospital of Philadelphia
- 84 shared
Rui Xiao
Nanchang University
- 66 shared
Kevin Meyers
- 66 shared
Shobha Natarajan
University of Pennsylvania
- 60 shared
Mary Beth F. Son
Boston Children's Hospital
- 43 shared
Peter A. Nigrović
Boston Children's Museum
- 41 shared
Esra Meidan
Harvard University
Education
- 2018
MSCE
University of Pennsylvania Perelman School of Medicine
- 2012
MD
University of Pennsylvania Perelman School of Medicine
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