John M. Inadomi

About

John M. Inadomi is a professor in the Department of Internal Medicine at the University of Utah Health, where he holds the Jon M. Huntsman Presidential Chair and serves as the Chair of the Department of Internal Medicine. He is a gastroenterologist with expertise in comparative effectiveness research, focusing on techniques to decrease mortality from esophageal adenocarcinoma and interventions to increase adherence to colorectal cancer screening tests. Dr. Inadomi received his undergraduate degree in mechanical engineering from MIT and his M.D. from the University of California, San Francisco, where he also completed his residency in internal medicine and fellowship in gastroenterology. He has been on the faculty of several institutions, including the University of New Mexico, the University of Michigan, UCSF, and the University of Washington, where he served as Division Head of Gastroenterology for 10 years. He is an associate editor of Gastroenterology, the President-Elect of the American Gastroenterological Association, and was set to become the President of the AGA in 2021. His research includes evaluating new endoscopic techniques, managing Barrett's esophagus, and addressing disparities in gastrointestinal cancer screening and outcomes.

Research topics

• Medicine
• Internal medicine
• Mathematics
• Demography
• Medical physics
• Environmental health
• Oncology
• Virology
• Intensive care medicine

Selected publications

• Screening and prevention of colorectal cancer

  BMJ · 2021 · 362 citations

  Senior authorCorresponding

  Mortality from colorectal cancer is reduced through screening and early detection; moreover, removal of neoplastic lesions can reduce cancer incidence. While understanding of the risk factors, pathogenesis, and precursor lesions of colorectal cancer has advanced, the cause of the recent increase in cancer among young adults is largely unknown. Multiple invasive, semi- and non-invasive screening modalities have emerged over the past decade. The current emphasis on quality of colonoscopy has impro…

  DOI

• Computational modelling suggests that Barrett’s oesophagus may be the precursor of all oesophageal adenocarcinomas

  Gut · 2020 · 68 citations

  Senior authorCorresponding

  OBJECTIVE: Barrett's oesophagus (BE) is a known precursor to oesophageal adenocarcinoma (OAC) but current clinical data have not been consolidated to address whether BE is the origin of all incident OAC, which would reinforce evidence for BE screening efforts. We aimed to answer whether all expected prevalent BE, diagnosed and undiagnosed, could account for all incident OACs in the US cancer registry data. DESIGN: We used a multiscale computational model of OAC that includes the evolutionary pro…

  DOI

• AGA Institute Rapid Review and Recommendations on the Role of Pre-Procedure SARS-CoV-2 Testing and Endoscopy

  Gastroenterology · 2020 · 53 citations

  DOI

• Characteristics of a cost-effective blood test for colorectal cancer screening

  JNCI Journal of the National Cancer Institute · 2024-06-06 · 24 citations

  articleOpen access

  BACKGROUND: Blood-based biomarker tests can potentially change the landscape of colorectal cancer (CRC) screening. We characterize the conditions under which blood test screening would be as effective and cost-effective as annual fecal immunochemical testing or decennial colonoscopy. METHODS: We used the 3 Cancer Information and Surveillance Modeling Network-Colon models to compare scenarios of no screening, annual fecal immunochemical testing, decennial colonoscopy, and a blood test meeting Cen…

  PublisherOA PDFDOI

• AGA Clinical Practice Guideline on Surveillance of Barrett’s Esophagus

  Gastroenterology · 2025-10-20 · 10 citations

  article
  PublisherDOI

Recent grants

• NIH Grant R01CA106773

  NIH · $1.4M · 2011

• Esophageal Cancer from Cells to Population: A Multiscale Approach

  NIH · $3.3M · 2013–2019

• Improving Gastrointestinal Disease Outcomes in Vulnerable Populations

  NIH · $1.8M · 2008–2022

Frequent coauthors

• Gary W. Falk

  209 shared

• Jacques Van Dam

  200 shared

• Joel H. Rubenstein

  University of Michigan–Ann Arbor

  145 shared

• David A. Lieberman

  Oregon Health & Science University

  139 shared

• Janusz Jankowski

  University College London

  130 shared

• Krish Ragunath

  125 shared

• Eamonn M.M. Quigley

  Cornell University

  122 shared

• Kenneth T. Wang

  Fuller Theological Seminary

  119 shared

Education

• B.S., Mechanical Engineering

  Massachusetts Institute of Technology (M.I.T.)

• M.D.

  University of California, San Francisco (UCSF)

Awards & honors

• Jon M. Huntsman Presidential Chair

Similar researchers at University of Utah

• John Erikson Yaph-56
• John F. Valentineh-55
• Michael J. Walkerh-45