
Hongjun Song
· David J. Mahoney ProfessorUniversity of Pennsylvania · Rehabilitation Medicine
Active 1994–2025
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About
Hongjun Song, Ph.D., is the David J. Mahoney Professor of Neurological Sciences in the Department of Neuroscience at the Perelman School of Medicine, University of Pennsylvania. His research focuses on two core topics: neural stem cell regulation and neurogenesis in the developing and adult mammalian brain, and epigenetic and epitranscriptomic mechanisms and their functions in the mammalian nervous system. His laboratory investigates how these processes influence neural function and addresses how dysfunction in these mechanisms may be involved in brain disorders. Dr. Song's work contributes to understanding the molecular and cellular basis of neurogenesis, neural circuitry, and brain disease, with a particular emphasis on epigenetic modifications such as m(6)A methylation and their roles in neural stem cell behavior and neurodevelopment.
Research topics
- Biology
- Cell biology
- Neuroscience
- Genetics
- Medicine
- Computer Science
- Pharmacology
- Psychology
- Internal medicine
- Chemistry
Selected publications
Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation
Cell stem cell · 2020 · 484 citations
Cell stem cell · 2020 · 456 citations
Nature Medicine · 2024 · 314 citations
Molecular landscapes of human hippocampal immature neurons across lifespan
Nature · 2022 · 304 citations
A nomenclature consensus for nervous system organoids and assembloids
Nature · 2022 · 283 citations
Recent grants
Epigenetic regulation of neurogenesis
NIH · $8.5M · 2016–2021
NIH · $805k · 2015
Continuous Neurogenesis in the Mammalian Hippocampus
NIH · $6.0M · 2020–2028
Frequent coauthors
- 1053 shared
Guo‐li Ming
- 149 shared
Kimberly M. Christian
University of Pennsylvania
- 124 shared
Junjie U. Guo
Affiliated Hospital of Qingdao University
- 110 shared
Ki‐Jun Yoon
Korea Advanced Institute of Science and Technology
- 95 shared
Yijing Su
- 93 shared
Fadi Jacob
Emory University
- 79 shared
Chun Zhong
- 74 shared
Kurt A. Sailor
Institut Pasteur
Labs
Song LabPI
Education
- 1992
B.S., Biology
Peking University, P.R. China
- 1995
M.A., Biology
Columbia University, New York
- 1998
Ph.D., Biology
University of California at San Diego, La Jolla
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