Dwight Rouse

About

Dwight Rouse is a Professor of Epidemiology and Obstetrics and Gynecology at Brown University. His research focuses on maternal-fetal medicine, including preeclampsia prevention, labor induction methods, neonatal outcomes, and gestational diabetes management. He has contributed to understanding the association between labor features and birth outcomes, as well as the cost-effectiveness of interventions in obstetrics. His work involves analyzing maternal and neonatal health outcomes, with an emphasis on improving clinical practices and maternal-fetal health through evidence-based research.

Research topics

• Medicine
• Internal medicine
• Virology
• Pathology
• Pediatrics

Selected publications

• Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection

  JAMA · 2023 · 831 citations

  Importance: SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms or other health effects occurring after acute infection, termed postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID. Characterizing PASC requires analysis of prospectively and uniformly collected data from diverse uninfected and infected individuals. Objective: To develop a definition of PASC using self-reported symptoms and describe PASC frequencies across cohorts, vaccination stat…

  PublisherOA PDFDOI

• Neurodevelopmental Outcomes After Late Preterm Antenatal Corticosteroids

  JAMA · 2024-04-24 · 56 citations

  articleOpen access

  Importance: The Antenatal Late Preterm Steroids (ALPS) trial changed clinical practice in the United States by finding that antenatal betamethasone at 34 to 36 weeks decreased short-term neonatal respiratory morbidity. However, the trial also found increased risk of neonatal hypoglycemia after betamethasone. This follow-up study focused on long-term neurodevelopmental outcomes after late preterm steroids. Objective: To evaluate whether administration of late preterm (34-36 completed weeks) corti…

  PublisherOA PDFDOI

• Differentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort

  Annals of Internal Medicine · 2024-08-12 · 42 citations

  articleOpen access

  BACKGROUND: There are currently no validated clinical biomarkers of postacute sequelae of SARS-CoV-2 infection (PASC). OBJECTIVE: To investigate clinical laboratory markers of SARS-CoV-2 and PASC. DESIGN: Propensity score-weighted linear regression models were fitted to evaluate differences in mean laboratory measures by prior infection and PASC index (≥12 vs. 0). (ClinicalTrials.gov: NCT05172024). SETTING: 83 enrolling sites. PARTICIPANTS: RECOVER-Adult cohort participants with or without SARS-…

  PublisherOA PDFDOI

• Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus

  Cochrane Database of Systematic Reviews · 2024-05-10 · 39 citations

  reviewOpen access

  BACKGROUND: Magnesium sulphate is a common therapy in perinatal care. Its benefits when given to women at risk of preterm birth for fetal neuroprotection (prevention of cerebral palsy for children) were shown in a 2009 Cochrane review. Internationally, use of magnesium sulphate for preterm cerebral palsy prevention is now recommended practice. As new randomised controlled trials (RCTs) and longer-term follow-up of prior RCTs have since been conducted, this review updates the previously published…

  PublisherOA PDFDOI

• Post–Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) After Infection During Pregnancy

  Obstetrics and Gynecology · 2024-07-11 · 13 citations

  articleOpen access

  OBJECTIVE: To estimate the prevalence of post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) after infection with SARS-CoV-2 during pregnancy and to characterize associated risk factors. METHODS: In a multicenter cohort study (NIH RECOVER [Researching COVID to Enhance Recovery]-Pregnancy Cohort), individuals who were pregnant during their first SARS-CoV-2 infection were enrolled across the United States from December 2021 to September 2023, either…

  PublisherOA PDFDOI

Recent grants

• Brown University/Women & Infants Hospital of Rhode Island (WIH) Center Application for the Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network

  NIH · $3.1M · 2001–2030

• NIH Grant U10HD040500

  NIH · $7.5M · 2016

• NIH Grant K24HD001375

  NIH · $553k · 2006

Frequent coauthors

• George R. Saade

  1982 shared

• Alan T. Tita

  Office of the Director

  1899 shared

• Michael W. Varner

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  1654 shared

• John M. Thorp

  1481 shared

• Brian M. Casey

  The University of Texas Southwestern Medical Center

  1470 shared

• Yoram Sorokin

  Wayne State University

  1322 shared

• Jay D. Iams

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  1320 shared

• Ronald J. Wapner

  New York Genome Center

  1277 shared

Education

• Ph.D., Epidemiology

  Brown University

  1990

• M.D., Obstetrics and Gynecology

  Brown University

  1984

• B.A., Biology

  Brown University

  1980

Similar researchers at Brown University

• Kenneth Mayerh-156
• Eunyoung Choh-105
• Jennifer Friedmanh-102