David W. Oslin

About

David W. Oslin, MD, is a Professor of Psychiatry and Staff Physician at the CPL. Michael J. Crescenz VA Medical Center in Philadelphia. He serves as the Director of the VISN 4 Mental Illness, Research, Education and Clinical Center (MIRECC) and is the Chief of Behavioral Health at the VA Medical Center. He is also the Vice Chair of Veterans Health in the Department of Psychiatry at the Perelman School of Medicine, University of Pennsylvania. His research expertise includes Geriatric and Addiction Psychiatry, with a focus on Veterans' behavioral health. Dr. Oslin's educational background includes a B.S. in Biology with a Mathematics minor from the University of Richmond, an M.D. from the University of Virginia, and he is affiliated with the Perelman School of Medicine at the University of Pennsylvania.

Research topics

• Psychiatry
• Medicine
• Biology
• Psychology
• Clinical psychology
• Medical emergency
• Pharmacology
• Internal medicine
• Genetics
• Physical therapy

Selected publications

• Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

  Biological Psychiatry · 2021 · 240 citations

  DOI

• Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder

  JAMA · 2022 · 177 citations

  1st authorCorresponding

  Importance: Selecting effective antidepressants for the treatment of major depressive disorder (MDD) is an imprecise practice, with remission rates of about 30% at the initial treatment. Objective: To determine whether pharmacogenomic testing affects antidepressant medication selection and whether such testing leads to better clinical outcomes. Design, Setting, and Participants: A pragmatic, randomized clinical trial that compared treatment guided by pharmacogenomic testing vs usual care. Partic…

  DOI

• Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans

  JAMA Psychiatry · 2022 · 55 citations

  Importance: Suicide is a leading cause of death; however, the molecular genetic basis of suicidal thoughts and behaviors (SITB) remains unknown. Objective: To identify novel, replicable genomic risk loci for SITB. Design, Setting, and Participants: This genome-wide association study included 633 778 US military veterans with and without SITB, as identified through electronic health records. GWAS was performed separately by ancestry, controlling for sex, age, and genetic substructure. Cross-ances…

  PublisherOA PDFDOI

• Change in suicidal ideation, depression, and anxiety following collaborative care in the community

  BMC Primary Care · 2024-07-05 · 12 citations

  articleOpen access

  BACKGROUND: The Collaborative Care Model (CoCM) increases access to mental health treatment and improves outcomes among patients with mild to moderate psychopathology; however, it is unclear how effective CoCM is for patients with elevated suicide risk. METHODS: We examined data from the Penn Integrated Care program, a CoCM program including an intake and referral management center plus traditional CoCM services implemented in primary care clinics within a large, diverse academic medical system.…

  PublisherOA PDFDOI

• Deep learning for identifying personal and family history of suicidal thoughts and behaviors from EHRs

  npj Digital Medicine · 2024-09-28 · 9 citations

  articleOpen access

  Personal and family history of suicidal thoughts and behaviors (PSH and FSH, respectively) are significant risk factors associated with suicides. Research is limited in automatic identification of such data from clinical notes in Electronic Health Records. This study developed deep learning (DL) tools utilizing transformer models (Bio_ClinicalBERT and GatorTron) to detect PSH and FSH in clinical notes derived from three academic medical centers, and compared their performance with a rule-based n…

  PublisherOA PDFDOI

Recent grants

• NIH Grant R01AA017164

  NIH · $3.0M · 2014

• NIH Grant K08MH001599

  NIH · $897k · 2005

• NIH Grant R01AA014851

  NIH · $3.3M · 2008

Frequent coauthors

• Shahrzad Mavandadi

  240 shared

• Joel E. Streim

  215 shared

• Lucinda B. Leung

  Center for the Study of Healthcare Provider Behavior

  184 shared

• Wilfred R. Pigeon

  United States Department of Veterans Affairs

  182 shared

• Ronald C. Kessler

  174 shared

• Edward P. Post

  170 shared

• Robert M. Bossarte

  University of South Florida

  170 shared

• Nathan A. Kimbrel

  Duke University

  165 shared

Similar researchers at University of Pennsylvania

• John Q. Trojanowskih-296
• Craig B. Thompsonh-277
• Daniel J Raderh-236