Daniel Rock

About

Daniel L. Rock is a Professor in the Department of Pathobiology at the College of Veterinary Medicine, University of Illinois Urbana-Champaign. He holds a PhD from Iowa State University and a BSE from Drake University, with postdoctoral training at the University of Pennsylvania-Wistar Institute. His research focuses on virology, including the study of viral pathogenesis and immune responses. He has contributed to the understanding of viral signaling pathways, such as the NF-kB signaling pathway, and has investigated cellular genes affecting virus infectivity. Dr. Rock teaches courses on Principles of Virology and Viral Pathogenesis, and his work has been published in scientific journals, advancing knowledge in veterinary and virological sciences.

Research topics

• Sociology
• Economics
• Virology
• Development economics
• Immunology
• Labour economics
• Economic growth
• Biology
• Medicine
• Geography

Selected publications

• GPTs are GPTs: An Early Look at the Labor Market Impact Potential of Large Language Models

  arXiv (Cornell University) · 2023 · 542 citations

  Senior authorCorresponding

  We investigate the potential implications of large language models (LLMs), such as Generative Pre-trained Transformers (GPTs), on the U.S. labor market, focusing on the increased capabilities arising from LLM-powered software compared to LLMs on their own. Using a new rubric, we assess occupations based on their alignment with LLM capabilities, integrating both human expertise and GPT-4 classifications. Our findings reveal that around 80% of the U.S. workforce could have at least 10% of their wo…

  PublisherOA PDFDOI

• Protective Immunity and New Vaccines for Lyme Disease

  Clinical Infectious Diseases · 2019-09-06 · 89 citations

  articleOpen access

  Lyme disease, caused by some Borrelia burgdorferi sensu lato, is the most common tick-borne illness in the Northern Hemisphere and the number of cases, and geographic spread, continue to grow. Previously identified B. burgdorferi proteins, lipid immunogens, and live mutants lead the design of canonical vaccines aimed at disrupting infection in the host. Discovery of the mechanism of action of the first vaccine catalyzed the development of new strategies to control Lyme disease that bypassed dire…

  PublisherOA PDFDOI

• Identification of T-cell epitopes in African swine fever virus CD2v and C-type lectin proteins

  Journal of General Virology · 2019-01-10 · 88 citations

  articleSenior author

  African swine fever (ASF) is an emerging disease threat for the swine industry worldwide. No ASF vaccine is available, and progress is hindered by lack of knowledge concerning the extent of ASF virus (ASFV) strain diversity and the viral antigens conferring type-specific protective immunity in pigs. Previously, we demonstrated that ASFV serotype-specific proteins CD2v (EP402R) and/or C-type lectin (EP153R) are important for protection against homologous ASF infection. Here, we identified six dis…

  PublisherDOI

• African Swine Fever Virus CD2v Protein Induces β-Interferon Expression and Apoptosis in Swine Peripheral Blood Mononuclear Cells

  Viruses · 2021-07-28 · 68 citations

  articleOpen accessSenior authorCorresponding

  African swine fever (ASF) is a hemorrhagic disease of swine characterized by massive lymphocyte depletion in lymphoid tissues due to the apoptosis of B and T cells, a process likely triggered by factors released or secreted by infected macrophages. ASFV CD2v (EP402R) has been implicated in viral virulence and immunomodulation in vitro; however, its actual function(s) remains unknown. We found that CD2v expression in swine PK15 cells induces NF-κB-dependent IFN-β and ISGs transcription and an ant…

  PublisherOA PDFDOI

• Thoughts on African Swine Fever Vaccines

  Viruses · 2021 · 55 citations

  1st authorCorresponding

  African swine fever (ASF) is an acute viral hemorrhagic disease of domestic swine with mortality rates approaching 100%. Devastating ASF outbreaks and continuing epidemics starting in the Caucasus region and now in the Russian Federation, Europe, China, and other parts of Southeast Asia (2007 to date) highlight its significance. ASF strain Georgia-07 and its derivatives are now endemic in extensive regions of Europe and Asia and are "out of Africa" forever, a situation that poses a grave if not…

  PublisherOA PDFDOI

Frequent coauthors

• G. F. Kutish

  University of Connecticut

  172 shared

• Zhiqiang Lu

  131 shared

• Claudio L. Afonso

  Oshkosh (United States)

  102 shared

• Gustavo Delhon

  University of Nebraska–Lincoln

  93 shared

• E. R. Tulman

  University of Connecticut

  66 shared

• Laszlo Zsak

  Agricultural Research Service

  50 shared

• Geoffrey J. Letchworth

  Agricultural Research Service

  37 shared

• Vladimı́r Beneš

  European Molecular Biology Laboratory

  36 shared

Labs

• Histology LaboratoryPI

  The Comparative Biosciences Histology Laboratory is a departmental laboratory that provides histologic technical services and support for teaching and research projects.

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