Christopher B Forrest

About

Christopher B Forrest, MD, PhD, is a Professor of Pediatrics (General Pediatrics) at the Children's Hospital of Philadelphia and a Professor at the Wharton School of Business. He holds a BA in Biology from Boston University, an MD from Boston University, and a PhD in Health Policy and Management from Johns Hopkins University. His research focuses on pediatric health, with significant contributions to understanding antihypertensive medication effectiveness in children with chronic kidney disease, blood pressure control in adolescents, and the use of pediatric learning health systems to characterize treatment responses in conditions such as lupus nephritis and recurrent glomerulosclerosis. Dr. Forrest is involved in multiple multicenter studies and has contributed to advancing clinical research methodologies, including data fitness assessment in clinical research and vaccine effectiveness in children. His work emphasizes improving pediatric healthcare outcomes through rigorous research and innovative health policy approaches.

Research topics

• Computer Science
• Medicine
• Algorithm
• Engineering
• Virology
• Internal medicine
• Statistics
• Mathematics
• Electrical engineering

Selected publications

• Assessment of 135 794 Pediatric Patients Tested for Severe Acute Respiratory Syndrome Coronavirus 2 Across the United States

  JAMA Pediatrics · 2020-11-23 · 245 citations

  articleOpen accessSenior author

  Importance: There is limited information on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing and infection among pediatric patients across the United States. Objective: To describe testing for SARS-CoV-2 and the epidemiology of infected patients. Design, Setting, and Participants: A retrospective cohort study was conducted using electronic health record data from 135 794 patients younger than 25 years who were tested for SARS-CoV-2 from January 1 through September 8, 2020. Da…

  PublisherOA PDFDOI

• PCORnet® 2020: current state, accomplishments, and future directions

  Journal of Clinical Epidemiology · 2020 · 189 citations

  1st authorCorresponding
  DOI

• Cardiac Complications After SARS-CoV-2 Infection and mRNA COVID-19 Vaccination — PCORnet, United States, January 2021–January 2022

  MMWR Morbidity and Mortality Weekly Report · 2022-04-01 · 149 citations

  articleOpen access

  Cardiac complications, particularly myocarditis and pericarditis, have been associated with SARS-CoV-2 (the virus that causes COVID-19) infection (1-3) and mRNA COVID-19 vaccination (2-5). Multisystem inflammatory syndrome (MIS) is a rare but serious complication of SARS-CoV-2 infection with frequent cardiac involvement (6). Using electronic health record (EHR) data from 40 U.S. health care systems during January 1, 2021-January 31, 2022, investigators calculated incidences of cardiac outcomes (…

  PublisherOA PDFDOI

• Trends in US Children’s Mortality, Chronic Conditions, Obesity, Functional Status, and Symptoms

  JAMA · 2025-07-07 · 43 citations

  articleOpen access1st authorCorresponding

  Importance: Recent scientific and policy statements suggest that child health may be worsening in the US. Objective: To determine how US children's health has been changing from 2007 to 2023 using multiple data collection methods and a comprehensive set of health indicators. Design, Setting, and Participants: Repeated, cross-sectional analyses using mortality statistics from the US and 18 comparator high-income nations from the Organisation for Economic Co-operation and Development (OECD18), 5 n…

  PublisherOA PDFDOI

• Understanding pediatric long COVID using a tree-based scan statistic approach: an EHR-based cohort study from the RECOVER Program

  JAMIA Open · 2023 · 27 citations

  Objectives: Post-acute sequalae of SARS-CoV-2 infection (PASC) is not well defined in pediatrics given its heterogeneity of presentation and severity in this population. The aim of this study is to use novel methods that rely on data mining approaches rather than clinical experience to detect conditions and symptoms associated with pediatric PASC. Materials and Methods: = 6545) SARS-CoV-2 infection. We used a tree-based scan statistic to identify potential condition clusters co-occurring more fr…

  PublisherOA PDFDOI

Recent grants

• NIH Grant U01AR05795602

  NIH · $1.0M · 2013

• NIH Grant K02HS000003

  NIH · $365k · 2004

• NIH Grant R13HS016070

  NIH · $27k · 2005

Frequent coauthors

• Dimitri Christakis

  University of Washington

  531 shared

• Jason P. Block

  Harvard Pilgrim Health Care

  526 shared

• Deepika Thacker

  Nemours Children's Health System

  509 shared

• Katherine B. Bevans

  508 shared

• Grace M. Lee

  Texas Children's Hospital

  502 shared

• Michael D. Kappelman

  498 shared

• Jon Puro

  Ochin

  492 shared

• Lindsay G. Cowell

  491 shared

Education

• PhD, Health Policy and Management

  Johns Hopkins University

  1995

• M.D., Medicine

  Boston University

  1986

• B.A., Biology

  Boston University

  1982

Similar researchers at University of Pennsylvania

• John Q. Trojanowskih-296
• Craig B. Thompsonh-277
• Daniel J Raderh-236