Christof Westenfelder
· Professor EmeritusVerifiedUniversity of Utah · Nephrology
Active 1974–2024
Research topics
- Endocrinology
- Pediatrics
- Medicine
- Internal medicine
Selected publications
Gitelman syndrome patient managed with amiloride during pregnancy and lactation
BMC Nephrology · 2024 · 2 citations
- Medicine
- Internal medicine
- Endocrinology
Gitelman Syndrome (GS) is a rare autosomal-recessive tubular disorder characterized by hypokalemia, hypomagnesemia, metabolic alkalosis, hyperreninemic hyperaldosteronism, and normotension. Management of GS during pregnancy is particularly challenging due to pregnancy-associated renal physiological changes and due to controversial safety profiles regarding teratogenicity of medications commonly used for GS management in non-pregnant patients. We report a case of a 20-year-old female patient diagnosed of GS who was treated with amiloride during pregnancy and lactation due to persistent hypokalemia resistant to oral supplementation therapy. Use of amiloride facilitated control of hypokalemia and hypomagnesemia in the mother without causing any noticeable side effects in the newborn.
Frequent coauthors
- 39 shared
Florian Tögel
Brigham and Women's Hospital
- 37 shared
Florian Toegel
Brigham and Women's Hospital
- 36 shared
Robert L. Baranowski
John T. Mather Memorial Hospital
- 30 shared
Zhuma Hu
- 29 shared
Anna Gooch
- 21 shared
José A.L. Arruda
- 20 shared
Axel R. Zander
- 19 shared
Claudia Lange
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