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Yang Gao

Yang Gao

· Professor of Microbiology

Ohio State University · Translational and Molecular Microbiology

Active 1994–2026

h-index34
Citations3.0k
Papers15388 last 5y
Funding—

Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.

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About

Yang Gao is an Assistant Professor in Cancer Biology & Genetics at The Ohio State University, affiliated with the Molecular, Cellular and Developmental Biology Program. Her research focuses on studying the tumor ecosystem, with particular emphasis on the heterogeneity of the immune landscape, mechanisms of therapeutic resistance, and the role of tumor–host interactions in cancer metastasis. Her work aims to uncover why treatment resistance and distant recurrence occur in solid tumors, especially breast cancer. Her laboratory has made significant contributions by demonstrating how myeloid cell heterogeneity contributes to immunotherapy resistance and revealing how the bone microenvironment influences breast cancer bone metastasis. Current projects in her lab involve exploring how neutrophil interferon-stimulated genes regulate the tumor immune microenvironment and response to immunotherapy, mapping immunosuppressive ecosystems that support breast cancer metastasis in major organs, and identifying mechanisms driving therapeutic resistance in metastatic disease. To achieve these goals, her team employs advanced technologies such as spatial transcriptomics, single-cell multi-omics, tumor immunology, and in vivo genetically engineered mouse models. Her research strives to generate insights that will translate into better therapies and improved outcomes for patients.

Research topics

  • Composite material
  • Materials science
  • Metallurgy
  • Condensed matter physics
  • Nanotechnology
  • Crystallography
  • Thermodynamics

Selected publications

Frequent coauthors

  • Hui‐Yuan Wang

    Wuhan University

    88 shared

  • Min Zha

    39 shared

  • Hai-Long Jia

    Jilin University

    34 shared

  • Yunzhi Wang

    The Ohio State University

    32 shared

  • Zhen-Ming Hua

    Hebei University of Technology

    30 shared

  • Min Zha

    Jilin University

    29 shared

  • Yongfeng Zhang

    22 shared

  • Dong Wang

    Xi'an Jiaotong University

    20 shared

Labs

  • Gao LabPI

Education

  • Ph.D., Materials Science and Engineering

    The Ohio State University

    2013

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