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Wendy M. Murray

Wendy M. Murray

· Professor of Biomedical Engineering

Northwestern University · Chemical Engineering

Active 1957–2024

h-index32
Citations6.5k
Papers20340 last 5y
Funding$4.4M

Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.

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About

Wendy M. Murray is a Professor of Biomedical Engineering and a Professor of Physical Medicine and Rehabilitation at Northwestern University. Her research focuses on developing biomechanical models that accurately represent the mechanical actions of the upper extremity muscles. She has shared these models and anatomical databases with the scientific community, which have been cited hundreds of times. Her main research application is to better understand and improve the function of the disabled upper limb, with relevance to basic motor control, control systems for exoskeletons and upper limb prosthetics, restoration of hand and arm function following cervical spinal cord injury, rehabilitation after stroke, orthopaedic interventions, and injury prevention in baseball pitching.

Research topics

  • Computer Science
  • Artificial Intelligence
  • Human–computer interaction
  • Simulation

Selected publications

  • A Musculoskeletal Model of the Hand and Wrist Capable of Simulating Functional Tasks

    IEEE Transactions on Biomedical Engineering · 2022-11-03 · 48 citations

    articleOpen accessSenior author

    OBJECTIVE: The purpose of this work was to develop an open-source musculoskeletal model of the hand and wrist and to evaluate its performance during simulations of functional tasks. METHODS: The current model was developed by adapting and expanding upon existing models. An optimal control theory framework that combines forward-dynamics simulations with a simulated-annealing optimization was used to simulate maximum grip and pinch force. Active and passive hand opening were simulated to evaluate…

  • Model-Based Control of Individual Finger Movements for Prosthetic Hand Function

    IEEE Transactions on Neural Systems and Rehabilitation Engineering · 2020 · 43 citations

    Prosthetic devices for hand difference have advanced considerably in recent years, to the point where the mechanical dexterity of a state-of-the-art prosthetic hand approaches that of the natural hand. Control options for users, however, have not kept pace, meaning that the new devices are not used to their full potential. Promising developments in control technology reported in the literature have met with limited commercial and clinical success. We have previously described a biomechanical mod…

  • Serial sarcomere number is substantially decreased within the paretic biceps brachii in individuals with chronic hemiparetic stroke

    Proceedings of the National Academy of Sciences · 2021-06-25 · 42 citations

    articleOpen accessSenior authorCorresponding

    Significance Serial sarcomere number determines a muscle’s length during maximum force production and its available length range for active force generation. Skeletal muscle length adapts to functional demands; for example, animal studies demonstrate that chronically shortened muscles decrease length by losing serial sarcomeres. This phenomenon has never been demonstrated in humans. Integrating multiscale imaging techniques, including two-photon microendoscopy, an innovative advance from traditi…

  • Motor Impairment–Related Alterations in Biceps and Triceps Brachii Fascicle Lengths in Chronic Hemiparetic Stroke

    Neurorehabilitation and neural repair · 2018-08-23 · 32 citations

    articleOpen access

    Poststroke deficits in upper extremity function occur during activities of daily living due to motor impairments of the paretic arm, including weakness and abnormal synergies, both of which result in altered use of the paretic arm. Over time, chronic disuse and a resultant flexed elbow posture may result in secondary changes in the musculoskeletal system that may limit use of the arm and impact functional mobility. This study utilized extended field-of-view ultrasound to measure fascicle lengths…

  • The Biomechanical Basis of the Claw Finger Deformity: A Computational Simulation Study

    The Journal Of Hand Surgery · 2019-06-25 · 18 citations

    articleOpen accessSenior authorCorresponding

Recent grants

Frequent coauthors

  • Michael S. Bednar

    Loyola University Medical Center

    59 shared
  • Eric J. Perreault

    Shirley Ryan AbilityLab

    57 shared
  • Jennifer A. Nichols

    University of Florida

    56 shared
  • Amy N. Adkins

    North Carolina State University

    56 shared
  • Benjamin I. Binder‐Markey

    Drexel University

    36 shared
  • Carrie L. Peterson

    Virginia Commonwealth University

    33 shared
  • Michael W. Keith

    MetroHealth Medical Center

    33 shared
  • Sarah J. Wohlman

    Northwestern University

    30 shared

Education

  • PhD, Biomedical Engineering

    Northwestern University

    1997
  • MS, Biomedical Engineering

    Northwestern University

    1992
  • BS, Mathematics

    University of Notre Dame

    1990

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