
Eric J. Perreault
· Vice President for ResearchNorthwestern University · Chemical Engineering
Active 1991–2026
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About
Eric J. Perreault is a Professor of Biomedical Engineering at Northwestern University. His research group focuses on understanding the neural and biomechanical factors involved in the normal control of multi-joint movement and posture, as well as how these factors are modified following neuromotor pathologies such as stroke and spinal cord injury. The goal of his research is to provide a scientific basis for understanding normal and pathological motor control that can be used to guide rehabilitative strategies and user interface development for restoring function to individuals with motor deficits. His work employs a combination of experimentation, computer simulations, and machine learning to achieve these objectives.
Research topics
- Computer Science
- Medicine
- Physics
- Physical therapy
- Artificial Intelligence
- Physical medicine and rehabilitation
- Classical mechanics
- Neuroscience
- Biology
- Mathematics
Selected publications
Consensus for experimental design in electromyography (CEDE) project: Amplitude normalization matrix
Journal of Electromyography and Kinesiology · 2020 · 318 citations
Estimating the dimensionality of the manifold underlying multi-electrode neural recordings
PLoS Computational Biology · 2021 · 80 citations
Senior authorCorrespondingIt is generally accepted that the number of neurons in a given brain area far exceeds the number of neurons needed to carry any specific function controlled by that area. For example, motor areas of the human brain contain tens of millions of neurons that control the activation of tens or at most hundreds of muscles. This massive redundancy implies the covariation of many neurons, which constrains the population activity to a low-dimensional manifold within the space of all possible patterns of…
Haptic Transparency and Interaction Force Control for a Lower Limb Exoskeleton
IEEE Transactions on Robotics · 2024-01-01 · 46 citations
articleControlling the interaction forces between a human and an exoskeleton is crucial for providing transparency or adjusting assistance or resistance levels. However, it is an open problem to control the interaction forces of lower-limb exoskeletons designed for unrestricted overground walking. For these types of exoskeletons, it is challenging to implement force/torque sensors at every contact between the user and the exoskeleton for direct force measurement. Moreover, it is important to compensate…
Journal of Electromyography and Kinesiology · 2024-03-13 · 38 citations
articleOpen accessThe diversity in electromyography (EMG) techniques and their reporting present significant challenges across multiple disciplines in research and clinical practice, where EMG is commonly used. To address these challenges and augment the reproducibility and interpretation of studies using EMG, the Consensus for Experimental Design in Electromyography (CEDE) project has developed a checklist (CEDE-Check) to assist researchers to thoroughly report their EMG methodologies. Development involved a mul…
Grand Challenges at the Interface of Engineering and Medicine
IEEE Open Journal of Engineering in Medicine and Biology · 2024-01-01 · 22 citations
articleOpen accessOver the past two decades Biomedical Engineering has emerged as a major discipline that bridges societal needs of human health care with the development of novel technologies. Every medical institution is now equipped at varying degrees of sophistication with the ability to monitor human health in both non-invasive and invasive modes. The multiple scales at which human physiology can be interrogated provide a profound perspective on health and disease. We are at the nexus of creating "avatars" (…
Recent grants
NIH · $621k · 2009
Stretch Reflex Contributions to Multijoint Coordination
NIH · $2.4M · 2006–2018
A primate model of an intra-cortically controlled FES prosthesis for grasp
NIH · $7.4M · 2006–2023
Frequent coauthors
- 167 shared
Daniel Ludvig
McCormick (United States)
- 70 shared
Levi J. Hargrove
Northwestern University
- 57 shared
Wendy M. Murray
- 48 shared
Robert F. Kirsch
Case Western Reserve University
- 44 shared
José L. Pons
Shirley Ryan AbilityLab
- 41 shared
François Hug
Université Côte d'Azur
- 39 shared
Yue Wen
Beijing Institute of Technology
- 38 shared
Emek Barış Küçüktabak
Shirley Ryan AbilityLab
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