Timo Prange

About

Timo Prange is an Associate Clinical Professor at the College of Veterinary Medicine at NC State University. His contact email is tprange@ncsu.edu. The page does not provide specific details about his research focus, background, or key contributions.

Research topics

• Medicine
• Biology
• Pharmacology
• Microbiology
• Veterinary medicine
• Computer Science
• Internal medicine
• Surgery
• Bioinformatics

Selected publications

• Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers

  PLoS ONE · 2019-10-04 · 38 citations

  articleOpen access

  Antimicrobial drug concentrations in the gastrointestinal tract likely drive antimicrobial resistance in enteric bacteria. Our objective was to determine the concentration of ceftiofur and its metabolites in the gastrointestinal tract of steers treated with ceftiofur crystalline-free acid (CCFA) or ceftiofur hydrochloride (CHCL), determine the effect of these drugs on the minimum inhibitory concentration (MIC) of fecal Escherichia coli, and evaluate shifts in the microbiome. Steers were administ…

  PublisherDOI

• Recovery of horses from general anesthesia after induction with propofol and ketamine versus midazolam and ketamine

  Journal of the American Veterinary Medical Association · 2018-06-18 · 21 citations

  article

  OBJECTIVE To evaluate quality of recovery from general anesthesia in horses after induction with propofol and ketamine versus midazolam and ketamine. DESIGN Prospective randomized crossover study. ANIMALS 6 healthy adult horses. PROCEDURES Horses were premedicated with xylazine (1.0 mg/kg [0.45 mg/lb], IV), and general anesthesia was induced with midazolam (0.1 mg/kg [0.045 mg/lb], IV) or propofol (0.5 mg/kg [0.23 mg/lb], IV), followed by ketamine (3.0 mg/kg [1.36 mg/lb], IV). Horses were endotr…

  PublisherDOI

• Dosing Regimen of Enrofloxacin Impacts Intestinal Pharmacokinetics and the Fecal Microbiota in Steers

  Frontiers in Microbiology · 2018-09-19 · 19 citations

  articleOpen access

  Objective: The intestinal concentrations of antimicrobial drugs that select for resistance in fecal bacteria of cattle are poorly understood. Our objective was to associate active drug concentrations in the intestine of steers with changes in the resistance profile and composition of the fecal microbiome. Methods: Steers were administered either a single high dose (12.5 mg/kg) or multiple 3 low dosemultiple doses (5 mg/kg) of enrofloxacin subcutaneously every 24 hours. Enrofloxacin and ciproflox…

  PublisherOA PDFDOI

• Effects of acellular equine amniotic allografts on the healing of experimentally induced full‐thickness distal limb wounds in horses

  Veterinary Surgery · 2019-08-06 · 12 citations

  article

  Abstract Objective To characterize the growth factors contained in equine amniotic membrane allograft (eAM; StemWrap scaffold and StemWrap+ injection) and to evaluate the effect of eAM on equine distal limb wound healing. Study design Prospective experimental controlled study. Sample population Eight adult horses. Methods Transforming growth factor (TGF)‐β1, vascular endothelial growth factor (VEGF), epidermal growth factor, platelet‐derived growth factor‐BB, and prostaglandin E 2 (PGE 2 ) conce…

  PublisherDOI

• Trachea

  Elsevier eBooks · 2018-09-28 · 10 citations

  book-chapter1st authorCorresponding
  PublisherDOI

Frequent coauthors

• Megan E. Jacob

  North Carolina State University

  17 shared

• Derek M. Foster

  North Carolina State University

  17 shared

• Mark G. Papich

  North Carolina State University

  13 shared

• Benjamin J. Callahan

  North Carolina State University

  12 shared

• Jennifer L. Halleran

  North Carolina State University

  8 shared

• Casey M. Theriot

  North Carolina State University

  8 shared

• Ronald E. Baynes

  North Carolina State University

  4 shared

• Hannah J. Slyvester

  North Carolina State University

  4 shared

Education

• Ph.D., Animal Science

  University of California, Davis

  2003

• M.S., Animal Science

  University of California, Davis

  1999

• B.S., Animal Science

  University of California, Davis

  1997

Similar researchers at North Carolina State University

• Edward Breitschwerdth-100
• B. Duncan X. Lascellesh-67
• Craig Harmsh-54