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Mark Papich

Mark Papich

North Carolina State University · Molecular Biomedical Sciences

Active 1977–2026

h-index63
Citations15.8k
Papers2.2k1246 last 5y
Funding

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About

Mark Papich is a faculty member associated with the College of Veterinary Medicine at NC State University. The page text does not provide specific details about his research focus, background, or key contributions. Therefore, no detailed biography can be extracted from the provided content.

Research topics

  • Pharmacology
  • Medicine
  • Internal medicine
  • Microbiology
  • Biology
  • Veterinary medicine
  • Gastroenterology
  • Intensive care medicine
  • Risk analysis (engineering)
  • Anesthesia

Selected publications

  • Patterns of antimicrobial drug use in veterinary primary care and specialty practice: A 6-year multi-institution study

    Journal of Veterinary Internal Medicine · 2021 · 37 citations

    BACKGROUND: Combatting antimicrobial resistance requires a One Health approach to antimicrobial stewardship including antimicrobial drug (AMD) use evaluation. Current veterinary AMD prescribing data are limited. OBJECTIVES: To quantify companion animal AMD prescribing in primary care and specialty practice across 3 academic veterinary hospitals with particular focus on third-generation cephalosporins, fluoroquinolones, and carbapenems. ANIMALS: Dogs and cats presented to 3 academic veterinary ho…

  • The effect of combined carprofen and omeprazole administration on gastrointestinal permeability and inflammation in dogs

    Journal of Veterinary Internal Medicine · 2020 · 37 citations

    BACKGROUND: Proton pump inhibitors (eg, omeprazole) commonly are administered concurrently with nonsteroidal anti-inflammatory drugs (NSAIDs; eg, carprofen) as prophylaxis to decrease the risk of gastrointestinal (GI) injury. However, evidence to support this practice is weak, and it might exacerbate dysbiosis and inflammation. HYPOTHESIS/OBJECTIVES: To evaluate the effect of carprofen alone or combined with omeprazole in dogs. We hypothesized that coadministration of omeprazole and carprofen wo…

  • Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID)

    Veterinary Dermatology · 2025-05-07 · 28 citations

    reviewOpen access

    BACKGROUND: Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. OBJECTIVES: To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin-resistant staphylococci. Guidance on diagnosing surface, superficial and deep pyoderma and their underlying primary causes, is included. Recommendations aim to optimise treatment outcomes while promoting responsible a…

  • Antimicrobial agent use in small animals what are the prescribing practices, use of PK‐PD principles, and extralabel use in the United States?

    Journal of Veterinary Pharmacology and Therapeutics · 2020 · 28 citations

    1st authorCorresponding

    In this review, the availability and deficiencies of current antimicrobial agents for companion animals in the United States are described. Although several active agents are FDA-approved for small animals, there are many unmet needs. These needs are greatest for cats, for the treatment of antibiotic drug-resistant infections, and to treat new or emerging pathogens that were not considered on older labels. The older agents approved before 1997 are often outdated, unavailable, or have inaccurate…

  • The effect of enrofloxacin on enteric Escherichia coli: Fitting a mathematical model to in vivo data

    PLoS ONE · 2020 · 14 citations

    Antimicrobial drugs administered systemically may cause the emergence and dissemination of antimicrobial resistance among enteric bacteria. To develop logical, research-based recommendations for food animal veterinarians, we must understand how to maximize antimicrobial drug efficacy while minimizing risk of antimicrobial resistance. Our objective is to evaluate the effect of two approved dosing regimens of enrofloxacin (a single high dose or three low doses) on Escherichia coli in cattle. We lo…

Frequent coauthors

Education

  • Ph.D., Veterinary Science

    North Carolina State University

    2002
  • M.S., Veterinary Science

    North Carolina State University

    1998
  • B.S., Animal Science

    University of California, Davis

    1996

Awards & honors

  • Zoetis Distinguished Veterinary Teacher Award
  • Faculty Award presented to the outstanding teacher by veteri…
  • Pfizer Award for Research Excellence
  • Excellence in Consensus Management by the Clinical and Labor…
  • Lloyd E.. Davis Award by the AAVPT

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