Ronald Baynes

About

Sarah Ho is the CVM Director of Student Engagement at the College of Veterinary Medicine at NC State University. Her role involves overseeing student development and engagement initiatives, fostering a supportive and collaborative campus community, and promoting student success and well-being. She is actively involved in creating opportunities for students to enrich their academic experience through extracurricular activities, study abroad programs, research projects, and community building. Her focus is on supporting the next generation of veterinary professionals by ensuring they have a comprehensive and enriching educational environment.

Research topics

• Pharmacology
• Medicine
• Biology
• Biotechnology
• Physical therapy
• Risk analysis (engineering)
• Environmental health
• Toxicology
• Business
• Management

Selected publications

• Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part I: Cattle and swine

  Journal of Veterinary Pharmacology and Therapeutics · 2020 · 48 citations

  Physiologically based pharmacokinetic (PBPK) models for chemicals in food animals are a useful tool in estimating chemical tissue residues and withdrawal intervals. Physiological parameters such as organ weights and blood flows are an important component of a PBPK model. The objective of this study was to compile PBPK-related physiological parameter data in food animals, including cattle and swine. Comprehensive literature searches were performed in PubMed, Google Scholar, ScienceDirect, and Pro…

  DOI

• Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part III: Sheep and goat

  Journal of Veterinary Pharmacology and Therapeutics · 2020 · 37 citations

  Abstract This report is the third in a series of studies that aimed to compile physiological parameters related to develop physiologically based pharmacokinetic (PBPK) models for drugs and environmental chemicals in food‐producing animals including swine and cattle (Part I), chickens and turkeys (Part II), and finally sheep and goats (the focus of this manuscript). Literature searches were conducted in multiple databases (PubMed, Google Scholar, ScienceDirect, and ProQuest), with data on relevan…

  DOI

• Producer and Veterinarian Perspectives towards Pain Management Practices in the US Cattle Industry

  Animals · 2021 · 29 citations

  Producers and veterinarians are considered responsible for improving animal welfare, as they are responsible for implementing practices that directly impact the animal's well-being. Most husbandry procedures performed in cattle do not include pain mitigation, and understanding challenges faced by these stakeholders to use analgesics is key in improving on-farm pain management strategies. Therefore, the objectives of this study were to explore producer and veterinarian perspectives on pain manage…

  DOI

• Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tissue and milk withdrawal intervals for per- and polyfluoroalkyl substances (PFAS)

  Food and Chemical Toxicology · 2023-09-26 · 15 citations

  articleOpen access

  Humans can be exposed to per- and polyfluoroalkyl substances (PFAS) through dietary intake from milk and edible tissues from food animals. This study developed a physiologically based pharmacokinetic (PBPK) model to predict tissue and milk residues and estimate withdrawal intervals (WDIs) for multiple PFAS including PFOA, PFOS and PFHxS in beef cattle and lactating dairy cows. Results showed that model predictions were mostly within a two-fold factor of experimental data for plasma, tissues, and…

  PublisherDOI

• Pharmacokinetics of intravenously and trans-dermally administered fluralaner in healthy laying shaver hens: fluralaner in chickens

  Poultry Science · 2023-12-09 · 8 citations

  articleOpen accessSenior authorCorresponding

  Ectoparasite infestations negatively affect both backyard and commercial chicken flocks in the US. Fluralaner is an isoxazoline shown to be efficacious in treating mite and bed bug infestations in poultry. Fluralaner is approved to treat fleas and ticks in dogs and cats in the US and to treat mite infestations of chickens in Europe and Australia; however, the use of fluralaner in poultry is not yet approved in the US. This study aimed to investigate the plasma fluralaner pharmacokinetic profile…

  PublisherDOI

Recent grants

• NIH Grant R01OH003669

  NIH · $2.3M · 2015

Frequent coauthors

• Jim E. Riviere

  Kansas State University

  154 shared

• Lisa A. Tell

  University of California, Davis

  43 shared

• Arthur L. Craigmill

  42 shared

• Geoffrey Smith

  35 shared

• C. McCombie

  Association for Regional and International Underground Storage

  25 shared

• F Secre- Tary

  UCL Australia

  25 shared

• John Evans

  25 shared

• Richmond Gordon

  Stellenbosch University

  25 shared

Labs

• CVM Pharmacology LabPI

Similar researchers at North Carolina State University

• Luke Borsth-37
• Siddhartha Thakurh-36
• Casey Therioth-35