Richard Y. Liu
· Assistant Professor of Chemistry and Chemical BiologyHarvard University · Chemistry
Active 1992–2026
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About
Richard Y. Liu, Ph.D., is an Assistant Professor in the Department of Chemistry and Chemical Biology at Harvard University. His research focuses on the development of innovative methods in chemistry and chemical biology, contributing to the advancement of the field through his expertise and leadership. Dr. Liu's background includes extensive education and research experience, and he is actively involved in mentoring a diverse group of postdoctoral fellows, graduate students, and undergraduate students, fostering a collaborative environment for scientific discovery.
Research topics
- Organic chemistry
- Combinatorial chemistry
- Chemistry
- Stereochemistry
- Medicinal chemistry
Selected publications
Reversible fluorenol photobases that perform CO2 capture and concentration from ambient air
Nature Chemistry · 2025-08-13 · 9 citations
articleSenior authorElectrifying industrial hydrogen peroxide production via soft interfacial molecular mediation
Nature Chemistry · 2025-09-22 · 7 citations
articleNi-Catalyzed Reductive Ring Contraction via Desulfurative Cross-Coupling
Journal of the American Chemical Society · 2025-07-10 · 4 citations
articleSenior authorCorrespondingThe construction of C–C bonds by contractive “deletion” of the sulfur atom from a C–S–C motif is a useful transformation for the synthesis of complex heterocycles. The transformation allows a user to take advantage of the nucleophilic reactivity of sulfur (e.g., for SNAr reactions) and remove that temporary atom at a late stage. A few homogeneous metal systems have been reported to mediate such desulfurizations, but under harsh conditions and, due to the formation of stable oligomeric sulfido co…
Accelerating the discovery of multicatalytic cooperativity
Nature · 2025-11-03 · 3 citations
articleOpen accessSynthesis of Diaryl Ethers by Formal Oxygen Insertion Between Suzuki–Miyaura Coupling Partners
ACS Catalysis · 2025-07-23 · 3 citations
articleSenior authorCorrespondingBecause of the broad availability of Suzuki–Miyaura cross-coupling partners (aryl (pseudo)halides and organoboron reagents), methods that can repurpose them for the divergent synthesis of many compound classes are attractive. We report a convenient three-component coupling strategy that formally inserts an oxygen atom into a Suzuki–Miyaura transformation to yield diaryl ethers. The reaction, involving in situ generation of an aryl borate intermediate by oxidation, provides a disconnection comple…
Frequent coauthors
- 38 shared
Stephen L. Buchwald
Massachusetts Institute of Technology
- 38 shared
Chun Fan
Temple University
- 38 shared
Kenneth S. Zuckerman
- 36 shared
Timothy M. Swager
Massachusetts Institute of Technology
- 32 shared
Roy Garcia
- 32 shared
Richard Jove
- 13 shared
Shao‐Xiong Lennon Luo
Massachusetts Institute of Technology
- 9 shared
Michael J. Aziz
Harvard University
Labs
Education
- 2002
Ph.D., Chemistry
Harvard University
- 1997
B.S., Chemistry
University of California, Berkeley
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