Paul Berg
Stanford University · Biochemistry
Active 1951–2024
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About
Professor Paul Berg is a distinguished member of the Department of Biochemistry at Stanford University, located at 279 Campus Drive, Beckman Center, Room B400, Stanford, CA. He has been recognized for his groundbreaking contributions to the field of biochemistry, particularly in the area of recombinant DNA technology. His work has significantly advanced scientific understanding and has been celebrated in various media, including a short film titled 'Life Recombined,' which explores the origins of recombinant DNA and highlights his pioneering role in this field. His research focus and contributions have had a profound impact on molecular biology and genetic engineering, establishing him as a leading figure in the scientific community.
Research topics
- Artificial Intelligence
- Machine Learning
- Data Mining
- Political Science
- Computer Science
- Public relations
- Psychology
Selected publications
A prudent path forward for genomic engineering and germline gene modification
Science · 2015-03-20 · 698 citations
articleOpen accessA framework for open discourse on the use of CRISPR-Cas9 technology to manipulate the human genome is urgently needed
Personal Reflections on the Origins and Emergence of Recombinant DNA Technology
Genetics · 2010-01-01 · 135 citations
articleOpen access1st authorCorrespondingThe emergence of recombinant DNA technology occurred via the appropriation of known tools and procedures in novel ways that had broad applications for analyzing and modifying gene structure and organization of complex genomes. Although revolutionary in their impact, the tools and procedures per se were not revolutionary. Rather, the novel ways in which they were applied was what transformed biology.
High-throughput method for analyzing methylation of CpGs in targeted genomic regions
Proceedings of the National Academy of Sciences · 2010-06-23 · 35 citations
articleOpen accessA unique microarray-based method for determining the extent of DNA methylation has been developed. It relies on a selective enrichment of the regions to be assayed by target amplification by capture and ligation (mTACL). The assay is quantitatively accurate, relatively precise, and lends itself to high-throughput determination using nanogram amounts of DNA. The measurements using mTACLs are highly reproducible and in excellent agreement with those obtained by sequencing (r = 0.94). In the presen…
Fred Sanger: A memorial tribute
Proceedings of the National Academy of Sciences · 2014-01-20 · 7 citations
articleOpen access1st authorCorrespondingProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Annual Review of Biochemistry · 2008-06-01 · 3 citations
article1st authorCorrespondingDevoted teachers and mentors during early childhood and adolescence nurtured my ambition to become a scientist, but it was not until I actually began doing experiments in college and graduate school that I was confident about that choice and of making it a reality. During my postdoctoral experiences and thereafter, I made several significant advances, most notably the discovery of the then novel acyl- and aminoacyl adenylates: the former as intermediates in fatty acyl coenzyme A (CoA) formation…
Recent grants
NIH · $4.7M · 1997
NIH · $443k · 1992
Frequent coauthors
- 40 shared
David S. Peabody
University of New Mexico
- 31 shared
Richard Mulligan
- 28 shared
John F. Morrow
- 28 shared
Suresh Subramani
University of California, San Diego
- 25 shared
Tom Kadesch
University of Pennsylvania
- 19 shared
Maxine Singer
- 17 shared
Michael J. McPhaul
Quest Diagnostics (United States)
- 16 shared
Andrew M. Lewis
University of Nottingham
Education
- 1952
Ph.D., Biochemistry
California Institute of Technology
- 1948
B.S., Chemistry
University of California, Los Angeles
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