Patricia Ann Cassano

About

Patricia Ann Cassano holds the position of The Alan D. Mathios Professor in the College of Human Ecology at Cornell University. She is a faculty member in the Department of Nutritional Sciences. Her research focuses on the nutritional genomics of lung phenotypes, nutrition translation and evidence synthesis, and nutrition for precision health. Her work integrates the study of how nutrition interacts with genetic factors affecting lung health, aiming to translate scientific findings into practical nutritional guidance tailored to individual health profiles. Through her expertise, she contributes to advancing the understanding of precision nutrition and its applications in improving health outcomes.

Research topics

• Internal medicine
• Medicine
• Cardiology
• Biology
• Virology
• Genetics

Selected publications

• Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults

  JAMA · 2021 · 272 citations

  Importance: Chronic lung diseases are a leading cause of morbidity and mortality. Unlike chronic obstructive pulmonary disease, clinical outcomes associated with proportional reductions in expiratory lung volumes without obstruction, otherwise known as preserved ratio impaired spirometry (PRISm), are poorly understood. Objective: To examine the prevalence, correlates, and clinical outcomes associated with PRISm in US adults. Design, Setting, and Participants: The National Heart, Lung, and Blood…

  PublisherOA PDFDOI

• Lung function impairment and risk of incident heart failure: the NHLBI Pooled Cohorts Study

  European Heart Journal · 2022 · 35 citations

  AIMS: The aim is to evaluate associations of lung function impairment with risk of incident heart failure (HF). METHODS AND RESULTS: Data were pooled across eight US population-based cohorts that enrolled participants from 1987 to 2004. Participants with self-reported baseline cardiovascular disease were excluded. Spirometry was used to define obstructive [forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) <0.70] or restrictive (FEV1/FVC ≥0.70, FVC <80%) lung physiology. The incide…

  PublisherOA PDFDOI

• Genetically predicted serum vitamin D and COVID-19: a Mendelian randomisation study

  BMJ Nutrition Prevention & Health · 2021 · 31 citations

  Senior authorCorresponding

  OBJECTIVES: To investigate causality of the association of serum vitamin D with the risk and severity of COVID-19 infection. DESIGN: Two-sample Mendelian randomisation study. SETTING: Summary data from genome-wide analyses in the population-based UK Biobank and SUNLIGHT Consortium, applied to meta-analysed results of genome-wide analyses in the COVID-19 Host Genetics Initiative. PARTICIPANTS: 17 965 COVID-19 cases including 11 085 laboratory or physician-confirmed cases, 7885 hospitalised cases…

  DOI

• Change in plasma α-tocopherol associations with attenuated pulmonary function decline and with CYP4F2 missense variation

  American Journal of Clinical Nutrition · 2022-01-14 · 5 citations

  articleOpen accessSenior authorCorresponding
  PublisherOA PDFDOI

• Vitamin D supplementation in pregnant or breastfeeding women or young children for preventing asthma

  Cochrane Database of Systematic Reviews · 2025-08-12 · 4 citations

  reviewOpen accessSenior author

  BACKGROUND: Randomised controlled studies evaluating vitamin D supplementation in pregnancy or early childhood for preventing childhood asthma have yielded inconclusive results. Previous systematic reviews of vitamin D for asthma prevention focused on studies comparing vitamin D to placebo or studies intervening in pregnancy, limiting the body of evidence. OBJECTIVES: Primary: to evaluate the efficacy of any vitamin D supplementation and high-dose vitamin D supplementation in early life, includi…

  PublisherOA PDFDOI

Recent grants

• NIH Grant R03HL095414

  NIH · $141k · 2011

• NIH Grant R01HL071022

  NIH · $3.1M · 2011

• NIH Grant R29HL045731

  NIH · $538k · 1998

Frequent coauthors

• George O'connor

  University of Wisconsin–Madison

  87 shared

• Stephanie J. London

  National Institute of Environmental Health Sciences

  84 shared

• Linda Youngman

  University of Oxford

  78 shared

• David Sparrow

  VA Boston Healthcare System

  56 shared

• Martin D. Tobin

  52 shared

• Augusto A. Litonjua

  Golisano Children's Hospital

  48 shared

• Pantel Vokonas

  Boston University

  48 shared

• Josée Dupuis

  Boston University

  47 shared

Labs

• Patricia Ann Cassano LabPI

Education

• Ph.D.

  Cornell University

Awards & honors

• Director of Cornell's PAHO/WHO Collaborating Centre on Nutri…
• Director of the Cochrane US Network Cornell Associate Center…
• Co-Director of the Joan Klein Jacobs Center for Precision Nu…

Similar researchers at Cornell University

• Robert Sternbergh-168
• Sander Kerstenh-106
• Savita Sastryh-95