Michael Fischbach

About

Michael Fischbach is the Liu (Liao) Family Professor of Bioengineering at Stanford University, an Institute Scholar of Stanford ChEM-H, and the director of the Stanford Microbiome Therapies Initiative. His laboratory studies the mechanisms of microbiome-host interactions. Fischbach received his Ph.D. in chemistry from Harvard in 2007 as a John and Fannie Hertz Foundation Fellow, where he studied the role of iron acquisition in bacterial pathogenesis and the biosynthesis of antibiotics. After two years as an independent fellow at Massachusetts General Hospital, he joined the faculty at UCSF, where he founded his lab before moving to Stanford in 2017. Fischbach is a recipient of numerous awards including the NIH Director's Pioneer and New Innovator Awards, an HHMI-Simons Faculty Scholars Award, a Fellowship from the David and Lucile Packard Foundation, a Medical Research Award from the W.M. Keck Foundation, a Burroughs Wellcome Fund Investigators award, and the Vannevar Bush Faculty Fellowship. He is also a co-founder of Revolution Medicines and Kelonia, and a co-founder and director of Azalea. Additionally, he serves on the scientific advisory boards of the Chan Zuckerberg Initiative, Stand Up to Cancer, and TCG Labs/Soleil Labs, and is an innovation partner at The Column Group.

Research topics

• Biology
• Microbiology
• Immunology
• Genetics
• Biochemistry
• Bioinformatics
• Medicine
• Internal medicine
• Endocrinology
• Ecology

Selected publications

• Dysbiosis-Induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation

  Cell Host & Microbe · 2020 · 831 citations

  DOI

• A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors

  Cell · 2020 · 725 citations

  DOI

• Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians

  Nature · 2021 · 596 citations

  DOI

• Design, construction, and in vivo augmentation of a complex gut microbiome

  Cell · 2022 · 260 citations

  Senior authorCorresponding
  PublisherOA PDFDOI

• Gut microbes impact stroke severity via the trimethylamine N-oxide pathway

  Cell Host & Microbe · 2021 · 153 citations

  DOI

Recent grants

• NIH Grant R01DK11017404

  NIH · $353k · 2020

• Core B: Analytical & Synthetic Chemistry Core

  NIH · $21.8M · 2019–2025

• NIH Grant M01RR001346

  NIH · $469k · 2008

Frequent coauthors

• Christopher T. Walsh

  Met Office

  61 shared

• Norman Talal

  59 shared

• Justin L. Sonnenburg

  Chan Zuckerberg Initiative (United States)

  59 shared

• Kazuki Nagashima

  Stanford University

  46 shared

• Stanley L. Hazen

  Cleveland Clinic Lerner College of Medicine

  35 shared

• Marnix H. Medema

  Wageningen University & Research

  34 shared

• Steven K. Higginbottom

  Stanford University

  34 shared

• Yasmine Belkaid

  National Institute of Allergy and Infectious Diseases

  33 shared

Education

• Ph.D., Bioengineering

  Stanford University

  2006

• M.S., Bioengineering

  University of California, San Diego

  2001

• B.S., Bioengineering

  University of California, San Diego

  1999

Awards & honors

• NIH Director's Pioneer and New Innovator Awards
• HHMI-Simons Faculty Scholars Award
• Fellowship for Science and Engineering from the David and Lu…
• Medical Research Award from the W.M. Keck Foundation
• Burroughs Wellcome Fund Investigators in the Pathogenesis of…

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• Paul Yockh-79
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