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Michael Alexander

Michael Alexander

· Assistant Professor of Family and Community Medicine

Ohio State University · Family Medicine

Active 1979–2018

h-index14
Citations710
Papers36
Funding—
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About

Michael Alexander, MD, is an assistant professor in the Department of Family Medicine at The Ohio State University College of Medicine. He has been a family physician practicing at OSU University Health Services since 2002, with clinical interests including ambulatory care and preventive medicine. Dr. Alexander is dedicated to providing personalized healthcare to his patients and actively participates in medical education, serving as an expert educator for longitudinal groups in LSI Part 1 since 2014 and as a faculty advisor to the OSU undergraduate student organization Alpha Epsilon Delta, the health preprofessional honor society, since 2004. His professional focus encompasses both patient care and medical education, contributing to the training of future healthcare professionals and serving the community where he resides.

Research topics

  • Medicine
  • Chemistry
  • Chromatography
  • Pharmacology
  • Biochemistry

Selected publications

  • The Gene Ontology resource: enriching a GOld mine

    Nucleic Acids Research · 2020 · 3820 citations

    • Computer Science
    • Information Retrieval
    • Computer Science

    The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium over the past two years. The new GO-CAM annotation framework was notably improved, and we formalized the model with a computational schema to check and validate the rapidly increasing repository of 2838 GO-CAMs. In addition, we describe the impacts of several collaborations to refine GO and report a 10% increase in the number of GO annotations, a 25% increase in annotated gene products, and over 9,400 new scientific articles annotated. As the project matures, we continue our efforts to review older annotations in light of newer findings, and, to maintain consistency with other ontologies. As a result, 20 000 annotations derived from experimental data were reviewed, corresponding to 2.5% of experimental GO annotations. The website (http://geneontology.org) was redesigned for quick access to documentation, downloads and tools. To maintain an accurate resource and support traceability and reproducibility, we have made available a historical archive covering the past 15 years of GO data with a consistent format and file structure for both the ontology and annotations.

    DOI

Frequent coauthors

Awards & honors

  • CAPS 1 Facilitator of the Year, The Ohio State University, 2…
  • The Gabel Award for Servant Leadership, The Ohio State Unive…

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