Guo-Liang Wang

About

Guo-Liang Wang is an Associate Chair, Endowed Professor of Plant Protection, and a OSU Distinguished Scholar at The Ohio State University. His role is within the Department of Plant Pathology, where he contributes to the academic and research missions of the college. His research focus is on plant protection, and he holds a prominent position in the department, indicating a significant contribution to the field of plant pathology and protection.

Research topics

• Computer Science
• Biology
• Artificial Intelligence
• Data Mining
• Political Science
• Machine Learning
• Genetics
• Algorithm
• Computational biology
• Evolutionary biology

Selected publications

• Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022

  Nucleic Acids Research · 2021 · 1088 citations

  The National Genomics Data Center (NGDC), part of the China National Center for Bioinformation (CNCB), provides a family of database resources to support global research in both academia and industry. With the explosively accumulated multi-omics data at ever-faster rates, CNCB-NGDC is constantly scaling up and updating its core database resources through big data archive, curation, integration and analysis. In the past year, efforts have been made to synthesize the growing data and knowledge, pa…

  DOI

• Machine Learning-Based Presymptomatic Detection of Rice Sheath Blight Using Spectral Profiles

  Plant Phenomics · 2020 · 65 citations

  = 105). These results suggest that machine learning models could be developed into tools to diagnose infected but asymptomatic plants based on spectral profiles at the early stages of disease development. While testing and validation in field trials are still needed, this technique holds promise for application in the field for disease diagnosis and management.

  DOI

• Natural variation in SBRR1 shows high potential for sheath blight resistance breeding in rice

  Nature Genetics · 2025-07-30 · 16 citations

  articleOpen access

  Sheath blight (ShB), caused by necrotrophic fungus Rhizoctonia solani, is one of the most serious rice diseases worldwide. To the best of our knowledge, no genes with high potential for rice ShB resistance breeding have been previously characterized. Here we identify a ShB resistance receptor-like kinase 1 (SBRR1) gene via a genome-wide association study. The SBRR1-R elite allele, containing a 256-bp insertion in its promoter, is preferentially present in indica varieties in geographical regions…

  PublisherOA PDFDOI

• Glutathione triggers leaf-to-leaf, calcium-based plant defense signaling

  Nature Communications · 2025-02-24 · 14 citations

  articleOpen accessCorresponding

  Animals rely on nervous systems to cope with environmental variability, whereas plants are characterized by lack of nervous system but still have evolved systemic communication systems through signaling molecules that trigger long-distance defense signaling events when encountered with environmental challenges. Here, our genetic screening of the previously constructed hairpin RNA-based Arabidopsis library identifies a glutathione (GSH)-deficient mutant that has high accumulation of glutamate (Gl…

  PublisherOA PDFDOI

• Occurrence and integrated control of major rice diseases in China

  New plant protection. · 2025-05-19 · 13 citations

  articleOpen access

  Abstract Rice is a vital staple food that sustains half of the world's population. However, it is constantly under threat from a variety of pathogens, including at least 13 fungi, 5 bacteria, 8 viruses, and 6 nematodes. These pathogens can significantly reduce rice yields, posing a serious risk to global food security. The increasing frequency of extreme weather events, coupled with the effects of climate change, has further exacerbated the spread and mutation of these pathogens, leading to a de…

  PublisherDOI

Recent grants

• AvrPiz-t-mediated suppression of PAMP- and effector-triggered immunity in rice by targeting host ubiqiutin proteasome system

  NSF · $634k · 2012–2016

Frequent coauthors

• Yuese Ning

  Institute of Plant Protection

  342 shared

• Chan Ho Park

  Department of Plant Biology

  260 shared

• Qi Xie

  195 shared

• Liangying Dai

  178 shared

• Houxiang Kang

  Chinese Academy of Agricultural Sciences

  172 shared

• Fan Zhang

  Zhengzhou University

  170 shared

• Maria Bellizzi

  The Ohio State University

  163 shared

• Wende Liu

  151 shared

Education

• Ph.D., Plant Pathology

  University of California, Davis

  1990

• M.S., Plant Pathology

  University of California, Davis

  1986

• B.S., Agricultural Chemistry

  National Taiwan University

  1983

Awards & honors

• Fellow, American Association for the Advancement of Science…
• Distinguished Senior Faculty Research Award, OARDC, College…
• Fellow, American Phytopathological Society (aps), August, 20…
• William E. Krauss Director's Award for Excellence in Graduat…
• Research Award of Merit, Gamma Sigma Delta, Honor Society of…

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