Marcelo Mollinari

About

Dr. Marcelo Mollinari is an Assistant Research Professor in the College of Agriculture and Life Sciences at NC State University, located in Ricks Hall. His primary research interests lie in genetic statistics and its applications in understanding complex biological processes of polyploid species, which are species with more than two paired sets of chromosomes. His work focuses on developing and applying statistical and computational strategies to decode the inheritance patterns in these species, with a particular emphasis on plant breeding.

Research topics

• Computer Science
• Genetics
• Biology
• Machine Learning
• Artificial Intelligence
• Computational biology
• Agronomy
• Biotechnology
• Evolutionary biology
• Botany

Selected publications

• Multiple QTL Mapping in Autopolyploids: A Random-Effect Model Approach with Application in a Hexaploid Sweetpotato Full-Sib Population

  Genetics · 2020 · 86 citations

  (L.) Lam. [Formula: see text], is an important autopolyploid species, both socially and economically. However, quantitative trait loci (QTL) mapping has remained limited due to its genetic complexity. Current fixed-effect models can fit only a single QTL and are generally hard to interpret. Here, we report the use of a random-effect model approach to map multiple QTL based on score statistics in a sweetpotato biparental population ('Beauregard' × 'Tanzania') with 315 full-sibs. Phenotypic data w…

  PublisherOA PDFDOI

• Sequencing depth and genotype quality: accuracy and breeding operation considerations for genomic selection applications in autopolyploid crops

  Theoretical and Applied Genetics · 2020 · 50 citations

  KEY MESSAGE: population of hexaploid sweetpotato and a diversity panel of 380 tetraploid potato, genotyped using different platforms to answer the following questions: (i) do polyploid crop breeders need to invest more for additional sequencing depth? (ii) how many markers are required to make selection decisions? (iii) does considering non-additive genetic effects improve predictive ability (PA)? (iv) does considering dosage or quantitative trait loci (QTL) offer significant improvement to PA?…

  PublisherOA PDFDOI

• Discovery of a major QTL for root-knot nematode (Meloidogyne incognita) resistance in cultivated sweetpotato (Ipomoea batatas)

  Theoretical and Applied Genetics · 2021 · 38 citations

  KEY MESSAGE: Utilizing a high-density integrated genetic linkage map of hexaploid sweetpotato, we discovered a major dominant QTL for root-knot nematode (RKN) resistance and modeled its effects. This discovery is useful for development of a modern sweetpotato breeding program that utilizes marker-assisted selection and genomic selection approaches for faster genetic gain of RKN resistance. The root-knot nematode [Meloidogyne incognita (Kofoid & White) Chitwood] (RKN) causes significant storage r…

  PublisherOA PDFDOI

• Meiosis in Polyploids and Implications for Genetic Mapping: A Review

  Genes · 2021 · 36 citations

  (oilseed rape) loci, which are known to play a crucial role in regulating meiosis. Finally, we exploited the consequences of chromosome pairing and recombination for genetic map construction in polyploids, highlighting two case studies of complex genomes: (i) modern sugarcane, which has a man-made genome harboring two subgenomes with some recombinant chromosomes; and (ii) hexaploid sweet potato, a naturally occurring polyploid. The recent inclusion of allelic dosage information has improved link…

  PublisherOA PDFDOI

• A public mid-density genotyping platform for alfalfa (Medicago sativa L.)

  Genetic Resources · 2023-10-13 · 22 citations

  articleOpen access

  Small public breeding programmes have many barriers to adopting technology, particularly creating and using genetic marker panels for genomic-based decisions in selection. Here we report the creation of a DArTag panel of 3,000 loci distributed across the alfalfa (Medicago sativa L.) genome for use in molecular breeding and genomic insight. The creation of this marker panel brings cost-effective and rapid genotyping capabilities to alfalfa breeding programmes. The open access provided by this pla…

  PublisherOA PDFDOI

Frequent coauthors

• Antônio Augusto Franco Garcia

  Universidade de São Paulo

  40 shared

• Anete Pereira de Souza

  Universidade Estadual de Campinas (UNICAMP)

  28 shared

• Guilherme da Silva Pereira

  Agricultural Research Service

  26 shared

• Thiago G. Marconi

  North Carolina State University

  21 shared

• Luciana Rossini Pinto

  Agronomical Institute of Campinas

  20 shared

• K. M. Oliveira

  18 shared

• G. Craig Yencho

  North Carolina State University

  18 shared

• Zhao‐Bang Zeng

  18 shared

Education

• PhD, Genetics

  Universidade de São Paulo Escola Superior de Agricultura Luiz de Queiroz Departamento de Genética

  2012

• Master, Genetics

  Universidade de São Paulo Escola Superior de Agricultura Luiz de Queiroz Departamento de Genética

  2008

• Agronomist, Genetics

  Universidade de São Paulo Escola Superior de Agricultura Luiz de Queiroz

  2006

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• Gavin Conanth-38