Mahsa Abassi

About

Dr. Mahsa Abassi is an Associate Professor in the Division of Endocrinology, Diabetes and Metabolism at the University of Minnesota. Her research focus is dedicated to the quality improvement of pituitary perioperative patient care and the management of various pituitary disorders. She is involved in clinical and research activities aimed at advancing understanding and treatment of pituitary conditions, contributing to the field through her expertise and leadership in this specialty.

Research topics

• Medicine
• Internal medicine
• Pathology
• Virology
• Immunology
• Dermatology
• Pharmacology
• Gastroenterology

Selected publications

• Cryptococcal meningitis

  Nature Reviews Disease Primers · 2023-11-09 · 115 citations

  reviewOpen access
  PublisherOA PDFDOI

• Oral Lipid Nanocrystal Amphotericin B for Cryptococcal Meningitis: A Randomized Clinical Trial

  Clinical Infectious Diseases · 2023 · 61 citations

  BACKGROUND: Amphotericin B is the gold standard treatment for severe mycoses. A new orally delivered, less-toxic formulation of amphotericin has been developed. METHODS: In our randomized clinical trial, we tested oral lipid nanocrystal (LNC) amphotericin B (MAT2203, Matinas Biopharma) vs intravenous (IV) amphotericin for human immunodeficiency virus-associated cryptococcal meningitis in 4 sequential cohorts. Two pilot cohorts assessed safety and tolerability (n = 10 each), and 2 cohorts assesse…

  PublisherOA PDFDOI

• The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19

  Annals of Internal Medicine · 2022 · 61 citations

  BACKGROUND: Levels of plasma SARS-CoV-2 nucleocapsid (N) antigen may be an important biomarker in patients with COVID-19 and enhance our understanding of the pathogenesis of COVID-19. OBJECTIVE: To evaluate whether levels of plasma antigen can predict short-term clinical outcomes and identify clinical and viral factors associated with plasma antigen levels in hospitalized patients with SARS-CoV-2. DESIGN: Cross-sectional study of baseline plasma antigen level from 2540 participants enrolled in t…

  DOI

• Diagnosis and management of cryptococcal meningitis in HIV-infected adults

  Clinical Microbiology Reviews · 2023-11-28 · 30 citations

  reviewOpen accessSenior author

  Cryptococcal meningitis is a leading cause of morbidity and mortality globally, especially in people with advanced HIV disease. Cryptococcal meningitis is responsible for nearly 20% of all deaths related to advanced HIV disease, with the burden of disease predominantly experienced by people in resource-limited countries. Major advancements in diagnostics have introduced low-cost, easy-to-use antigen tests with remarkably high sensitivity and specificity. These tests have led to improved diagnost…

  PublisherOA PDFDOI

• Efficacy and Safety of Ensovibep for Adults Hospitalized With COVID-19

  Annals of Internal Medicine · 2022 · 30 citations

  BACKGROUND: Ensovibep (MP0420) is a designed ankyrin repeat protein, a novel class of engineered proteins, under investigation as a treatment of SARS-CoV-2 infection. OBJECTIVE: To investigate if ensovibep, in addition to remdesivir and other standard care, improves clinical outcomes among patients hospitalized with COVID-19 compared with standard care alone. DESIGN: Double-blind, randomized, placebo-controlled, clinical trial. (ClinicalTrials.gov: NCT04501978). SETTING: Multinational, multicent…

  DOI

Frequent coauthors

• Joshua Rhein

  University of Minnesota

  199 shared

• David B. Meya

  Infectious Diseases Institute

  185 shared

• Darlisha A Williams

  155 shared

• David R. Boulware

  University of Minnesota

  133 shared

• Abdu Musubire

  Makerere University

  121 shared

• Katelyn A Pastick

  University of Minnesota

  106 shared

• Lillian Tugume

  Infectious Diseases Institute

  100 shared

• Kathy Huppler Hullsiek

  University of Minnesota

  98 shared

Labs

• Araki LabPI

Awards & honors

• Clinical Excellence, 2020
• Peter G. Pappas Young Investigators Award, 2018

Similar researchers at University of Minnesota

• Emmanuel Antonarakish-99
• Elizabeth Seaquisth-53
• Stuart Amateauh-32