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Lin Chen

Lin Chen

· Assistant Professor

University of Illinois Urbana-Champaign · Educational Psychology

Active 1998–2025

h-index29
Citations2.6k
Papers10744 last 5y
Funding—

Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.

Faculty pageLab pageWebsite
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Research topics

  • Biology
  • Cancer research
  • Cell biology
  • Chemistry
  • Medicine

Selected publications

  • Microglial PGC-1α protects against ischemic brain injury by suppressing neuroinflammation

    Genome Medicine · 2021-03-26 · 199 citations

    articleOpen access

    BACKGROUND: Neuroinflammation and immune responses occurring minutes to hours after stroke are associated with brain injury after acute ischemic stroke (AIS). PPARγ coactivator-1α (PGC-1α), as a master coregulator of gene expression in mitochondrial biogenesis, was found to be transiently upregulated in microglia after AIS. However, the role of microglial PGC-1α in poststroke immune modulation remains unknown. METHODS: PGC-1α expression in microglia from human and mouse brain samples following i…

    PublisherOA PDFDOI

  • Recent Development of Active Ingredients in Mouthwashes and Toothpastes for Periodontal Diseases

    Molecules · 2021-04-01 · 127 citations

    reviewOpen accessSenior authorCorresponding

    Periodontal diseases like gingivitis and periodontitis are primarily caused by dental plaque. Several antiplaque and anti-microbial agents have been successfully incorporated into toothpastes and mouthwashes to control plaque biofilms and to prevent and treat gingivitis and periodontitis. The aim of this article was to review recent developments in the antiplaque, anti-gingivitis, and anti-periodontitis properties of some common compounds in toothpastes and mouthwashes by evaluating basic and cl…

    PublisherOA PDFDOI

  • Line-based Instance Segmentation for Robust and Automatic MRI Spine Scan Planning

    Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · 2025-09-16

    article

    Motivation: To enhance the accuracy and efficiency of automated spine view planning, this approach can be seamlessly adapted for MRI instruments operating at various field strengths. Goal(s): To develop an intelligent prescription method for transverse scanning planes of intervertebral discs (IVDs) on sagittal spine images, applicable across various magnetic field strengths. Approach: We employed an instance segmentation approach for the detection and segmentation of intervertebral discs (IVDs).…

    PublisherDOI

Frequent coauthors

  • Warner C. Greene

    Gladstone Institutes

    29 shared

  • Margaret A. Shipp

    Dana-Farber Cancer Institute

    16 shared

  • Xiaodong Yang

    14 shared

  • Yoshiaki Ito

    13 shared

  • Acacia Lamb

    Children's Hospital of The King's Daughters

    12 shared

  • Frank Beier

    Western University

    11 shared

  • Eric R. Fearon

    11 shared

  • Matthias Buck

    Case Western Reserve University

    11 shared

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