About

Larry Phelan is a Professor of Entomology at The Ohio State University, based in the Wooster Science Building. His research focuses on entomology, contributing to the department's broader efforts in understanding insect biology and ecology. As a faculty member, he is involved in teaching, research, and outreach activities related to entomology, supporting the university's mission to advance knowledge and education in this field.

Research topics

• Bioinformatics
• Biochemistry
• Ecology
• Biology
• Botany
• Zoology

Selected publications

• Non-targeted metabolomics reveals differences in the gut metabolic profile of the fall armyworm strains when feeding different food sources

  Journal of Insect Physiology · 2022 · 12 citations

  • Biology
  • Zoology
  • Botany
  DOI

• NON-TARGETED METABOLOMICS REVEAL DIFFERENCES IN THE METABOLIC PROFILE OF THE FALL ARMYWORM STRAINS WHEN FEEDING DIFFERENT FOOD SOURCES

  bioRxiv (Cold Spring Harbor Laboratory) · 2022

  • Biology
  • Zoology
  • Botany

  ABSTRACT Spodoptera frugiperda , the fall armyworm (FAW), is an important polyphagous agricultural pest feeding on nearly 350 host plants. FAW is undergoing incipient speciation with two well-characterized host-adapted strains, the “corn” ( CS ) and “rice” ( RS ) strains, which are morphologically identical but carry several genes under positive selection for host adaptation. We used non-targeted metabolomics based on gas chromatography/mass spectrometry to identify differences in metabolite profiles of the larval gut of CS and RS feeding on different host plants. Larvae were fed on artificial diet, maize, rice, or cotton leaves from eclosion to the sixth instar, when they had their midgut dissected for the analysis. This study revealed that the midgut metabolome of FAW varied due to larval diet and differed between the FAW host-adapted strains. Additionally, we identified several candidate metabolites that may be involved in the adaptation of CS and RS to their host plants. Our findings provide clues toward the gut metabolic activities of the FAW strains.

  DOI

Frequent coauthors

• Nathalia Cavichiolli de Oliveira

  Universidade Católica Dom Bosco

  2 shared

• Fernando L. Cônsoli

  Universidade de São Paulo

  2 shared

• Parwinder S. Grewal

  The University of Texas Rio Grande Valley

  2 shared

• Ruisheng An

  University of Tennessee at Knoxville

  2 shared

• Sophia Kazakova

  Centers for Disease Control and Prevention

  2 shared

• Bernard T. Garfinkel

  BJC HealthCare

  2 shared

• Carlos Alberto Labate

  Methodist University of Piracicaba

  2 shared

• Linda K. McDougal

  Centers for Disease Control and Prevention

  1 shared

Labs

• Larry Phelan LabPI

Similar researchers at Ohio State University

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