Kenneth J Lee

About

Kenneth J Lee is a professor at the University of Chicago in the Department of Neurology. His research focuses on neurocritical care, particularly in the management of critically ill neurological and neurosurgical patients. His clinical and research interests include neuromonitoring, management of traumatic brain injury, and neurocritical care ethics. He has contributed to the understanding of brain blood flow testing, intracranial pressure management, and the ethical considerations surrounding brain death and end-of-life care in neurocritical settings. Dr. Lee has been involved in multiple research activities, including NIH-funded clinical trials, and has published extensively on topics related to neurotrauma, brain injury management, and critical care neurology.

Research topics

• Chemistry
• Nanotechnology
• Materials science
• Mechanics
• Condensed matter physics
• Geometry
• Physics
• Crystallography
• Biology
• Biophysics

Selected publications

• Parkinson’s disease-associated mutations in α-synuclein alters its lipid-bound state

  Biophysical Journal · 2024-05-03 · 8 citations

  articleOpen accessSenior authorCorresponding
  PublisherOA PDFDOI

• Binding equations for the lipid composition dependence of peripheral membrane-binding proteins

  Biophysical Journal · 2024-03-02 · 8 citations

  articleOpen accessSenior authorCorresponding
  PublisherOA PDFDOI

• MFG-E8: a model of multiple binding modes associated with ps-binding proteins

  The European Physical Journal E · 2023-11-01 · 5 citations

  articleSenior authorCorresponding
  PublisherDOI

• Multiscale geometry and mechanics of lipid monolayer collapse

  Current topics in membranes · 2021 · 4 citations

  DOI

• Structure of polymer-capped gold nanorods binding to model phospholipid monolayers

  Journal of Physics Materials · 2021 · 3 citations

  Abstract We report an experimental study of the structure of polymer-capped gold nanorods (AuNRs) binding to model phospholipid monolayers to elucidate the mechanism that drives the insertion of the AuNRs into phospholipid membranes. The experimental system consists of four different cases of AuNRs interacting with lipid monolayers: cationic and anionic polymer-capped AuNRs suspended in the pure water subphase of Langmuir monolayers of zwitterionic and anionic phospholipids, separately. Liquid s…

  DOI

Recent grants

• Interactions of Cholesterol and Gangliosides with Lipids

  NSF · $1.0M · 2009–2014

• Lipid-Cholesterol Interactions in Membranes

  NSF · $562k · 2006–2009

• The Interplay Between Membrane Structure and Protein Interactions

  NSF · $1.1M · 2014–2019

Frequent coauthors

• Alan J. Waring

  94 shared

• Shelli L. Frey

  Gettysburg College

  58 shared

• Yuji Ishitsuka

  53 shared

• Jarosław Majewski

  U.S. National Science Foundation

  47 shared

• Robert I. Lehrer

  42 shared

• J. Michael Henderson

  Institut Pasteur

  40 shared

• Binhua Lin

  University of Chicago

  39 shared

• Kathleen D. Cao

  University of Chicago

  36 shared

Labs

• Kenneth J Lee LabPI

Education

• M.D.

  University of Chicago

• B.S.

  University of Chicago

Awards & honors

• 2011 European Diploma in Intensive Care, European Society of…

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• Nicholas G. Hatsopoulosh-57
• Richard Kraigh-47