John Carroll Murray

The skin transcriptome in hidradenitis suppurativa uncovers an antimicrobial and sweat gland gene signature which has distinct overlap with wounded skin

PLoS ONE · 2019-05-06 · 73 citations

Hidradenitis suppurativa (HS) is a debilitating chronic inflammatory skin disease resulting in non-healing wounds affecting body areas of high hair follicle and sweat gland density. The pathogenesis of HS is not well understood but appears to involve dysbiosis-driven aberrant activation of the innate immune system leading to excessive inflammation. Marked dysregulation of antimicrobial peptides and proteins (AMPs) in HS is observed, which may contribute to this sustained inflammation. Here, we a…

Impact of COVID-19 on Cardiovascular Testing in the United States Versus the Rest of the World

JACC. Cardiovascular imaging · 2021 · 39 citations

OBJECTIVES: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-U.S. institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. BACKGROUND: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mor…

Thymic stromal lymphopoietin controls hair growth

Stem Cell Reports · 2022-02-24 · 6 citations

-mediated deletion of Tslpr in HFSCs inhibited both wound-induced and exogenous TSLP-induced hair growth. Our data highlight a novel function for TSLP in regulation of hair follicle activity during homeostasis and wound healing.

Improvement of Recalcitrant Folliculitis Decalvans With Tirzepatide: A Case Report

Cureus · 2024 · 3 citations

Folliculitis decalvans (FD) is a chronic inflammatory alopecia characterized by painful, scarring lesions and recurrent flares, often complicated by secondary bacterial infections. Despite the use of topical and systemic anti-inflammatory or antimicrobial therapies, FD remains challenging to manage, with limited therapeutic advancements. We report a case of recalcitrant FD in a man in his 40s who experienced significant symptom improvement and hair regrowth following the initiation of tirzepatid…

Counting real characters after Gallagher

arXiv (Cornell University) · 2023-01-03

Let $G$ be a finite group, let $N$ be a normal subgroup of $G$ and let $θ$ be an irreducible character of $N$. We count the real irreducible characters of $G$ lying over $θ$