Jennifer Barrett
· Assistant Professor of Biomedical Sciences and PathobiologyVirginia Tech · Department of Biomedical Sciences and Pathobiology
Active 1960–2026
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About
Jennifer G. Barrett, DVM, PhD, DACVS, DACVSMR, is the Theodora Ayer Randolph Professor of Equine Surgery at the Marion duPont Scott Equine Medical Center, part of the Virginia-Maryland College of Veterinary Medicine at Virginia Tech. Her research interests focus on tendon, ligament, and cartilage healing, as well as stem cell and platelet-rich plasma therapies and tissue regeneration. Dr. Barrett earned her DVM from Cornell University in 2002, her Ph.D. in Molecular Cellular and Developmental Biology from Yale University in 1999, and holds additional degrees from Yale and Dartmouth College. She is board-certified by the American College of Veterinary Surgeons and the American College of Veterinary Sports Medicine and Rehabilitation. Her professional experience includes serving as the Theodora Ayer Randolph Professor of Equine Surgery since 2014 at the Marion duPont Scott Equine Medical Center, where she has also been an Associate Professor of Equine Surgery since 2013. She has held positions as an Affiliate Assistant Professor at George Mason University and an Adjunct Assistant Professor at Wake Forest University. Dr. Barrett's prior roles include Assistant Professor of Equine Surgery and postdoctoral research positions at the University of Illinois at Urbana-Champaign and the University of Wisconsin-Madison, as well as internships and research assistantships at Rood and Riddle Equine Hospital and Cornell University. Her professional memberships encompass the North American…
Research topics
- Medicine
- Cell biology
- Biology
- Anatomy
- Immunology
Selected publications
Frontiers in Veterinary Science · 2016-09-09 · 70 citations
articleOpen accessSenior authorOBJECTIVE: To report clinical findings and outcomes for 55 dogs with supraspinatus tendinopathy (ST) treated with adipose-derived progenitor cells and platelet-rich plasma (ADPC-PRP) therapy. METHODS: Medical records of client-owned dogs diagnosed with ST that were treated with ADPC-PRP combination therapy were reviewed from 2006 to 2013. Data collected included signalment, medical history, limb involvement, prior treatments, physical and orthopedic examination, objective temporospatial gait ana…
The Potential of Mesenchymal Stem Cells to Treat Systemic Inflammation in Horses
Frontiers in Veterinary Science · 2020-01-21 · 48 citations
reviewOpen accessSenior authorCorrespondingOne hallmark of mesenchymal stem cells (MSCs) is the ability to differentiate into multiple tissue types which assists in tissue regeneration. Another hallmark of MSCs is their potent anti-inflammatory and immunomodulatory properties and the potential to treat inflammatory, immune-mediated, and ischemic conditions. In equine practice, MSCs have shown efficacy in the treatment of musculoskeletal disorders such as tendinopathy, meniscal tears and cartilage injury. However, there are many equine di…
Journal of Tissue Engineering · 2019-01-01 · 40 citations
articleOpen accessSenior authorCorrespondingAdult tissue stem cells have shown promise for the treatment of debilitating tendon injuries. However, few comparisons of stem cells from different tissue sources have been made to determine the optimum stem cell source for treating tendon. Moreover, it is likely that the application of tenogenic growth factors will improve tendon stem cell treatments further, and a comprehensive comparison of a number of growth factors is needed. Thus far, different types of stem cells cannot be evaluated in a…
Stem Cells and Development · 2019-06-13 · 33 citations
articleSenior authorCorrespondingMesenchymal stem cells (MSCs) have great potential to improve clinical outcomes for many inflammatory and degenerative diseases either through intravenously delivered MSCs or through mobilization and migration of endogenous MSCs to injury sites, termed "stem cell homing." Stem cell homing involves the processes of attachment to and transmigration through endothelial cells lining the vasculature and migration through the tissue stroma to a site of injury or inflammation. Although the process of l…
Aligned Nanofiber Topography Directs the Tenogenic Differentiation of Mesenchymal Stem Cells
Applied Sciences · 2017-01-06 · 26 citations
articleOpen accessSenior authorCorrespondingTendon is commonly injured, heals slowly and poorly, and often suffers re-injury after healing. This is due to failure of tenocytes to effectively remodel tendon after injury to recapitulate normal architecture, resulting in poor mechanical properties. One strategy for improving the outcome is to use nanofiber scaffolds and mesenchymal stem cells (MSCs) to regenerate tendon. Various scaffold parameters are known to influence tenogenesis. We designed suspended and aligned nanofiber scaffolds with…
Frequent coauthors
- 55 shared
M. N. Gooseff
Institute of Arctic and Alpine Research
- 48 shared
Peter M. Brophy
Aberystwyth University
- 46 shared
Ross A. Virginia
Dartmouth College
- 42 shared
Diana H. Wall
- 30 shared
Cristina Takacs‐Vesbach
- 30 shared
Byron J. Adams
Brigham Young University
- 26 shared
Eric R. Sokol
- 26 shared
S. Craig Cary
University of Waikato
Education
Other, Veterinary Medicine
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Ph.D., Not specified in the provided HTML
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Awards & honors
- Zoetis Award for Veterinary Research Excellence (2017)
- Clinical Research Award, LRP National Institutes of Health (…
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