About

Hiba Haider is an Associate Professor at the University of Chicago, within the Department of Neurology. She is an adult epileptologist and serves as the Director of Critical Care EEG at UChicago Medicine. Her research interests include studying modifiable predictors of outcomes in status epilepticus, and she leverages informatics and implementation science to optimize inpatient care for this condition. Dr. Haider's educational background includes an MD from Aga Khan University Medical College in Karachi, Pakistan, and specialized training in neurology and clinical neurophysiology at Emory University School of Medicine. She has received multiple awards for her service and research, including the 2023 Distinction in Service Award from the American Clinical Neurophysiology Society and the 2018 Faculty Award from Emory University Department of Neurology. Her research activities involve clinical phenotyping, surveillance of status epilepticus, and development of EEG interpretation techniques, contributing significantly to the field of neurocritical care and epilepsy.

Research topics

• Medicine
• Internal medicine
• Gastroenterology
• Immunology
• Biology
• Genetics
• Oncology

Selected publications

• Risk of Colorectal Cancer in Serrated Polyposis Syndrome: A Systematic Review and Meta-analysis

  Clinical Gastroenterology and Hepatology · 2021 · 36 citations

  • Medicine
  • Internal medicine
  • Oncology
  DOI

• Efficacy of various endoscopic modalities in detecting dysplasia in ulcerative colitis: A systematic review and network meta-analysis

  World Journal of Gastrointestinal Endoscopy · 2020 · 17 citations

  • Medicine
  • Internal medicine
  • Gastroenterology

  BACKGROUND: Longstanding ulcerative colitis (UC) is associated with an increased risk of colonic neoplasia. Various endoscopic modalities, such as chromoendoscopy (CE), narrow band imaging (NBI) and random biopsy have been introduced for surveillance, however, there exists a paucity of direct comparisons between them. We aimed to conduct a network meta-analysis of randomized controlled trials (RCTs) performed for surveillance of neoplasia in UC. AIM: To provide a comparative evaluation of the efficacy of the above-mentioned various modalities. METHODS: We searched MEDLINE/PubMed, Web of Science, Embase, Google Scholar and Cochrane Central Registry through May 2016 for RCTs evaluating the efficacy of endoscopic modalities for surveillance of neoplasia in UC. The primary outcomes of interest were dysplasia (low- or high-grade) detection rates per biopsy and per patient, and dysplasia numbers per patient. Studies were simultaneously analyzed using a random-effects network meta-analysis under the Bayesian framework to identify the modality with the highest dysplasia detection rate. The best ranking probability for the dysplasia detection rate was analyzed by surface under the cumulative ranking (SUCRA) technique. RESULTS: Six prospective RCTs of a total 1038 patients were identified. We identified 4 different modalities; white light (WL) high definition (HD) or standard definition (SD), CE HD, and NBI HD. For dysplasia per biopsy, direct meta-analysis showed superiority of NBI HD over WL HD and CE HD over WL SD. Network meta-analysis demonstrated the rank order of best modality as NBI HD, CE HD, WL HD and WL SD with close SUCRA scores of the first two. For dysplasia per patient, direct meta-analyses showed equivocal results between each modality. Network meta-analysis demonstrated the rank order of best modality as WL HD, NBI HD, CE HD and WL SD with small differences of the SUCRA score among the first two. For dysplasia numbers per patient, direct meta-analysis showed superiority of CE HD over WL SD. Network meta-analysis demonstrated the rank order of best modality as WL HD, NBI HD, CE HD, and WL SD with small differences of the SUCRA score among the first three. CONCLUSION: We demonstrated that there were small differences among WL HD, NBI HD, and CE HD, while WL SD was inferior, in detecting dysplasia in UC.

  DOI

• Population Difference in Allele Frequency of HLA-C*05 and Its Correlation with COVID-19 Mortality

  Viruses · 2020 · 60 citations

  • Immunology
  • Biology
  • Medicine

  BACKGROUND: coronavirus disease 2019 (COVID-19) causes severe illness including cytokine storms, but mortality among countries differs largely. In the present study, we investigated the association between human leukocyte antigen (HLA) class I, which plays a major role in susceptibility to viral infections, and the mortality of COVID-19. METHODS: , expressed on natural killer (NK) cells, and differential mortality to historic pandemics were analyzed. RESULTS: , which in combination cause NK cell-induced hyperactive immune response. Countries with similar ethnic and/or geographic background responded in a similar pattern to each pandemic. CONCLUSIONS: strongly correlated with COVID-19 mortality. Host genetic variance of innate immunity may contribute to the difference in mortality among various countries and further investigation using patient samples is warranted.

  DOI

Frequent coauthors

• Atsushi Sakuraba

  Hokkaido University

  35 shared

• Dejan Mićić

  University of Chicago

  33 shared

• Akihiro Yamada

  Astellas Pharma (Japan)

  33 shared

• Fukiko Komaki

  University of Chicago

  32 shared

• Yuga Komaki

  Kagoshima University

  32 shared

• Nolan W. Faust

  Northwestern University

  26 shared

• Joel Pekow

  University of Chicago

  9 shared

• David T. Rubin

  6 shared

Education

• M.D.

  University of Chicago

• B.S.

  University of Chicago

Awards & honors

• 2023 Distinction in Service Award, American Clinical Neuroph…
• 2018 Distinction in Service Faculty Award, Emory University,…
• 2014 Young Investigator Travel Award, American Clinical Neur…
• 2008 Young Investigator Award, American Epilepsy Society

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