Guiyun Yan

About

Dr. Guiyun Yan is a Chancellor’s Professor in the Department of Population Health & Disease Prevention at the University of California, Irvine, with a focus on global health. He earned his Ph.D. in Biology from the University of Vermont in 1994. Dr. Yan's research centers on the epidemiology of vector-borne diseases and vector biology. His work includes evaluating the effects of environmental modifications and invasive vectors on malaria transmission and disease burden in Africa, assessing the impact of urbanization on dengue transmission and vector ecology in Asia, studying the ecological genetics of insecticide resistance, and developing adaptive and locally tailored vector intervention strategies. Dr. Yan also serves as the program director for a Center of Excellence for Malaria Research (ICEMR) in Ethiopia and Kenya, funded by the National Institutes of Health (NIH), and is the project director for a global infectious disease training program funded by the Fogarty International Center.

Research topics

• Biology
• Ecology
• Immunology
• Veterinary medicine
• Medicine
• Genetics
• Toxicology
• Environmental health
• Zoology

Selected publications

• Resting behaviour of malaria vectors in highland and lowland sites of western Kenya: Implication on malaria vector control measures

  PLoS ONE · 2020 · 73 citations

  BACKGROUND: Understanding the interactions between increased insecticide resistance and resting behaviour patterns of malaria mosquitoes is important for planning of adequate vector control. This study was designed to investigate the resting behavior, host preference and rates of Plasmodium falciparum infection in relation to insecticide resistance of malaria vectors in different ecologies of western Kenya. METHODS: Anopheles mosquito collections were carried out during the dry and rainy seasons…

  DOI

• Patterns of human exposure to early evening and outdoor biting mosquitoes and residual malaria transmission in Ethiopia

  Acta Tropica · 2021 · 72 citations

  DOI

• Phenotypic, genotypic and biochemical changes during pyrethroid resistance selection in Anopheles gambiae mosquitoes

  Scientific Reports · 2020 · 62 citations

  The directional selection for insecticide resistance due to indiscriminate use of insecticides in public health and agricultural system favors an increase in the frequency of insecticide-resistant alleles in the natural populations. Similarly, removal of selection pressure generally leads to decay in resistance. Past investigations on the emergence of insecticide resistance in mosquitoes mostly relied on field survey of resistance in vector populations that typically had a complex history of exp…

  DOI

• Urban malaria in sub-Saharan Africa: a scoping review of epidemiologic studies

  Malaria Journal · 2025-04-19 · 13 citations

  reviewOpen access

  BACKGROUND: Malaria control in African cities faces challenges mainly due to unplanned urbanization and the spread of Anopheles stephensi. Urbanization is changing malaria dynamics, driven by environmental changes and population growth, with nearly 70% of people projected to live in urban areas by 2050. This scoping review maps the epidemiology of urban malaria in sub-Saharan Africa, identifying research gaps and guiding strategies for control and elimination. METHODS: A structured search across…

  PublisherOA PDFDOI

• Esterase-Mediated Pyrethroid Resistance in Populations of an Invasive Malaria Vector Anopheles stephensi from Ethiopia

  Genes · 2024-12-15 · 7 citations

  articleOpen accessSenior author

  Background: The swift expansion of the invasive malaria vector Anopheles stephensi throughout Africa presents a major challenge to malaria control initiatives. Unlike the native African vectors, An. stephensi thrives in urban settings and has developed resistance to multiple classes of insecticides, including pyrethroids, organophosphates, and carbamates. Methods: Insecticide susceptibility tests were performed on field-collected An. stephensi mosquitoes from Awash Sebac Kilo, Ethiopia, to asses…

  PublisherOA PDFDOI

Recent grants

• NIH Grant R03TW007360

  NIH · $118k · 2009

• NIH Grant R56AI050243

  NIH · $508k · 2008

• A Novel Hydrology-based Malaria Transmission Model and Field Applications

  NIH · $418k · 2022–2025

Frequent coauthors

• Guofa Zhou

  University of California, Irvine

  136 shared

• Andrew K. Githeko

  135 shared

• Ming‐Chieh Lee

  University of California, Irvine

  116 shared

• Daibin Zhong

  University of California, Irvine

  95 shared

• James W. Kazura

  Case Western Reserve University

  64 shared

• Harrysone Atieli

  Maseno University

  63 shared

• Delenasaw Yewhalaw

  Jimma University

  56 shared

• Xiaoming Wang

  54 shared

Labs

• Yan LabPI

  Ecology of African malaria vectors; Malaria epidemiology; Dengue vector biology in Asia

Education

• Ph.D., Environmental Health Sciences

  University of California, Los Angeles

  2003

• M.S., Environmental Health Sciences

  University of California, Los Angeles

  1999

• B.S., Environmental Health Sciences

  University of California, Los Angeles

  1997

Awards & honors

• ICEMR Award of Excellence, NIAID, NIH, 2011
• Chancellor’s Fellow, UC Irvine, 2019

Similar researchers at University of California, Irvine

• Karen Lindsayh-71
• Oladele Ogunseitanh-48
• Michelle Fortierh-40