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Franco Laghi

University of Chicago · Rheumatology

Active 1989–2025

h-index46
Citations10.4k
Papers22557 last 5y
Funding—

Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.

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About

Franco Laghi is an Assistant Professor of Medicine in the Department of Medicine at The University of Chicago. His research focuses on respiratory support, swallowing physiology, airway protection, and respiratory-swallow patterns in adults. His work includes systematic reviews and studies on noninvasive respiratory support, physiologic principles of intubation in hypoxemic patients, and the role of diaphragm ultrasound imaging in mechanical ventilation discontinuation. Dr. Laghi has also contributed to understanding sleep EEG patterns in weaning from mechanical ventilation, respiratory testing in patients with amyotrophic lateral sclerosis and COPD, and the management of insomnia in COPD patients. His research extends to physical rehabilitation in the ICU, outcomes of mechanically ventilated COVID-19 patients, and case reports on complex pulmonary conditions. His publications demonstrate a focus on improving respiratory care and understanding the physiological mechanisms underlying respiratory and airway management.

Research topics

  • Medicine
  • Internal medicine
  • Intensive care medicine
  • Virology
  • Anesthesia
  • Engineering
  • Mechanical engineering
  • Cardiology
  • Pediatrics

Selected publications

  • Caution about early intubation and mechanical ventilation in COVID-19

    Annals of Intensive Care · 2020 · 290 citations

    DOI

  • <i>P</i><sub>aO<sub>2</sub></sub>/<i>F</i><sub>IO<sub>2</sub></sub>ratio: the mismeasure of oxygenation in COVID-19

    European Respiratory Journal · 2021-03-01 · 42 citations

    letterOpen accessSenior author

    We read with interest A. Tulaimat's letter concerning our recent editorial in the European Respiratory Journal [1]. A. Tulaimat makes several insightful comments on problems with criteria used for entering patients into randomised controlled trials of noninvasive ventilation. Among these, he notes that arterial-to-inspired oxygen ( P aO2/ F IO2) ratio varied between 170 and 400 among enrollees [2]. P aO2 is the most precise measurement of patient oxygenation in COVID-19, but its accuracy is corr…

    PublisherOA PDFDOI

  • Monitoring Respiratory Muscle Function

    2021-01-01 · 18 citations

    book-chapter1st authorCorresponding
    PublisherDOI

  • Air Hunger Far Exceeds Dyspnea Sense of Effort during Mechanical Ventilation and a Weaning Trial

    American Journal of Respiratory and Critical Care Medicine · 2024-12-16 · 12 citations

    articleOpen access

    Abstract Rationale No systematic investigation into dyspnea in patients receiving prolonged ventilation (&amp;gt;21 d) after recovering from critical illness has been published. Objectives We sought to determine the magnitude, nature, and pathophysiological basis of dyspnea during an unassisted-breathing trial in patients receiving prolonged ventilation. Methods Dyspnea intensity and descriptor selection were investigated in 27 patients receiving prolonged ventilation during a 60-minute unassist…

    PublisherOA PDFDOI

  • SARS-CoV-2 infection increases risk of acute kidney injury in a bimodal age distribution

    BMC Nephrology · 2022 · 10 citations

    BACKGROUND: Hospitalized patients with SARS-CoV2 develop acute kidney injury (AKI) frequently, yet gaps remain in understanding why adults seem to have higher rates compared to children. Our objectives were to evaluate the epidemiology of SARS-CoV2-related AKI across the age spectrum and determine if known risk factors such as illness severity contribute to its pattern. METHODS: Secondary analysis of ongoing prospective international cohort registry. AKI was defined by KDIGO-creatinine only crit…

    DOI

Recent grants

Frequent coauthors

  • Martin J. Tobin

    RML Specialty Hospital

    190 shared

  • Amal Jubran

    RML Specialty Hospital

    115 shared

  • Hameeda Shaikh

    54 shared

  • Eileen G. Collins

    University of Illinois Chicago

    49 shared

  • Martin Dres

    26 shared

  • Arzu Topeli̇

    Hacettepe University

    26 shared

  • Joan C. Stoklosa

    University of Baltimore

    22 shared

  • Howard Belzberg

    University of Southern California

    18 shared

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