About

David T. Rubin is the Joseph B. Kirsner Professor of Medicine, Professor of Pathology, Chief of the Section of Gastroenterology, Hepatology & Nutrition, and Director of the Inflammatory Bowel Disease Center at the University of Chicago Medicine. He earned his medical degree with honors from The University of Chicago Pritzker School of Medicine, where he also completed his residency in internal medicine and fellowships in gastroenterology and clinical medical ethics. Rubin is an associate faculty member at the MacLean Center for Clinical Medical Ethics, an associate investigator at the University of Chicago Comprehensive Cancer Center, and a member of the University of Chicago Committee on Clinical Pharmacology and Pharmacogenomics. He has served as the immediate past Chair of the National Scientific Advisory Committee of the Crohn’s & Colitis Foundation and is the current Chair of the International Organization for the Study of IBD. His research focuses on disease modification in inflammatory bowel disease (IBD), including clinical trial designs, novel measures of inflammation, prevention of adverse outcomes, and quality of life in IBD. Rubin has received multiple awards for his clinical research and contributions to the field, including the Sherman Prize for Excellence in Crohn’s and Colitis, the UChicago Michael Reese Lectureship Award, and the Arthur H. Rubenstein Mentorship in Academic Medicine Award. He is also the Editor-in-Chief of the ACG On-Line Education Universe and has authored or edited numerous publications, including guidelines for ulcerative colitis management.

Research topics

• Internal medicine
• Medicine
• Gastroenterology
• Intensive care medicine
• Surgery
• Physical therapy
• Computer Science
• Immunology
• Biology
• Physical medicine and rehabilitation
• Virology
• Dermatology
• Chemistry
• Pathology
• World Wide Web
• Family medicine
• Microbiology
• Environmental health

Selected publications

• Su1661 GUSELKUMAB IS SAFE AND EFFECTIVE IN PATIENTS WITH CROHN’S DISEASE AND PAST EXPOSURE TO RISANKIZUMAB

  Gastroenterology · 2026-05-01

  articleSenior author
  PublisherDOI

• Mo1680 IMPROVEMENT IN ANXIETY SYMPTOMS IS MORE STRONGLY ASSOCIATED WITH GOOD SLEEP QUALITY IN ADULTS WITH INFLAMMATORY BOWEL DISEASE THAN IMPROVEMENT IN DEPRESSIVE SYMPTOMS, SYMPTOMATIC REMISSION, OR BIOCHEMICAL REMISSION

  Gastroenterology · 2026-05-01

  articleSenior author
  PublisherDOI

• Mo1671 THE PATIENT HEALTH QUESTIONNAIRE-9 DETECTS MODERATE DEPRESSIVE SYMPTOMS AND SUICIDAL IDEATION IN ADULT PATIENTS WITH INFLAMMATORY BOWEL DISEASE WHO WOULD NOT HAVE SCREENED POSITIVE BY THE PATIENT HEALTH QUESTIONNAIRE-2 ALONE

  Gastroenterology · 2026-05-01

  articleSenior author
  PublisherDOI

• Mo1523 IMPACT OF UP TO 3 YEARS OF CONTINUOUS ETRASIMOD TREATMENT: LONG-TERM EFFICACY RESULTS FROM THE ELEVATE UC OPEN-LABEL EXTENSION

  Gastrointestinal Endoscopy · 2026-05-01

  articleSenior author
  PublisherDOI

• 485 MATERNAL FOOD ADDITIVE INTAKE REPROGRAM OFFSPRING IMMUNITY VIA GUT MICROBIOTA-INDUCED IMPAIRMENT OF HISTIDINE METABOLISM (MOMMY-IBD STUDY)

  Gastrointestinal Endoscopy · 2026-05-01

  article
  PublisherDOI

• Characterizing Engagement With a Mobile Health Application Designed for Adolescents and Young Adults With Sickle Cell Disease: Findings From the COMETS Study

  Pediatric Blood & Cancer · 2026-03-17

  article

  The transition from pediatric to adult care for adolescents with sickle cell disease is marked by increased disease complexity. The effectiveness of a mobile health (mHealth) application in supporting transition was evaluated in the COMETS (Community Health Worker and Mobile Health Programs) trial. Participant engagement with the mHealth application was evaluated in this study. The component SMS Text Messages had the highest number of unique users (n = 94), and interaction with application health and behavior tracking challenges had the highest median interactions per user (median = 4.5). Most participants engaged with the mHealth application at least once, yet engagement varied across components and declined over the course of the study.

  PublisherDOI

• Mo1523 IMPACT OF UP TO 3 YEARS OF CONTINUOUS ETRASIMOD TREATMENT: LONG-TERM EFFICACY RESULTS FROM THE ELEVATE UC OPEN-LABEL EXTENSION

  Gastroenterology · 2026-05-01

  articleSenior author
  PublisherDOI

• Mo1680 IMPROVEMENT IN ANXIETY SYMPTOMS IS MORE STRONGLY ASSOCIATED WITH GOOD SLEEP QUALITY IN ADULTS WITH INFLAMMATORY BOWEL DISEASE THAN IMPROVEMENT IN DEPRESSIVE SYMPTOMS, SYMPTOMATIC REMISSION, OR BIOCHEMICAL REMISSION

  Gastrointestinal Endoscopy · 2026-05-01

  articleSenior author
  PublisherDOI

• Mo1671 THE PATIENT HEALTH QUESTIONNAIRE-9 DETECTS MODERATE DEPRESSIVE SYMPTOMS AND SUICIDAL IDEATION IN ADULT PATIENTS WITH INFLAMMATORY BOWEL DISEASE WHO WOULD NOT HAVE SCREENED POSITIVE BY THE PATIENT HEALTH QUESTIONNAIRE-2 ALONE

  Gastrointestinal Endoscopy · 2026-05-01

  articleSenior author
  PublisherDOI

• Sa1525 PROGNOSTIC VALUE OF EARLY ENDOSCOPIC FINDINGS IN ILEAL POUCH-ANAL ANASTAMOSIS OUTCOMES

  Gastroenterology · 2026-05-01

  article
  PublisherDOI

Frequent coauthors

• Joel Pekow

  University of Chicago

  182 shared

• Laurent Peyrin‐Biroulet

  Université de Lorraine

  174 shared

• David Choi

  University of Chicago

  174 shared

• Julián Panés

  Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

  173 shared

• Remo Panaccione

  165 shared

• Séverine Vermeire

  162 shared

• Russell D. Cohen

  158 shared

• Silvio Danese

  Vita-Salute San Raffaele University

  156 shared

Labs

• Rubin LabPI

Education

• M.D.

  University of Chicago Pritzker School of Medicine

  1994

• Other, Internal Medicine

  University of Chicago Pritzker School of Medicine

  1997

• Other, Gastroenterology

  University of Chicago Pritzker School of Medicine

  2001

• B.S., Honors Biology

  University of Illinois

  1990

Awards & honors

• ACG’s Governor’s Award of Excellence in Clinical Research (2…
• Sherman Prize for Excellence in Crohn’s and Colitis (2020)
• UChicago Michael Reese Lectureship Award (2023)
• Arthur H. Rubenstein Mentorship in Academic Medicine Award (…