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David O. Meltzer

· Chief of the Section of Hospital Medicine Director of the Center for Health and the Social Sciences Chair of the Committee on Clinical and Translational Science Professor of Medicine

University of Chicago · Global Health

Active 1961–2026

h-index66
Citations17.1k
Papers32865 last 5y
Funding$79.4M2 active

Academic metrics are sourced from OpenAlex and public funding records; values may differ from Google Scholar.

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Research topics

  • Medicine
  • Internal medicine
  • Biology
  • Virology
  • Immunology
  • Mathematical physics
  • Psychology
  • Quantum mechanics
  • Gastroenterology
  • Physics

Selected publications

  • Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results

    JAMA Network Open · 2020 · 526 citations

    1st authorCorresponding

    Importance: Vitamin D treatment has been found to decrease the incidence of viral respiratory tract infection, especially in patients with vitamin D deficiency. Whether vitamin D is associated with coronavirus disease 2019 (COVID-19) incidence is unknown. Objective: To examine whether the last vitamin D status before COVID-19 testing is associated with COVID-19 test results. Design, Setting, and Participants: This retrospective cohort study at an urban academic medical center included patients w…

  • Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses

    Science Advances · 2022 · 138 citations

    The spread of SARS-CoV-2 and ongoing COVID-19 pandemic underscores the need for new treatments. Here we report that cannabidiol (CBD) inhibits infection of SARS-CoV-2 in cells and mice. CBD and its metabolite 7-OH-CBD, but not THC or other congeneric cannabinoids tested, potently block SARS-CoV-2 replication in lung epithelial cells. CBD acts after viral entry, inhibiting viral gene expression and reversing many effects of SARS-CoV-2 on host gene transcription. CBD inhibits SARS-CoV-2 replicatio…

  • Association of Vitamin D Deficiency and Treatment with COVID-19 Incidence

    medRxiv (Cold Spring Harbor Laboratory) · 2020 · 99 citations

    1st authorCorresponding

    IMPORTANCE: Vitamin D treatment has been found to decrease incidence of viral respiratory tract infection, especially in vitamin D deficiency. It is unknown whether COVID-19 incidence is associated with vitamin D deficiency and treatment. OBJECTIVE: To examine whether vitamin D deficiency and treatment are associated with testing positive for COVID-19. DESIGN: Retrospective cohort study Setting: University of Chicago Medicine Participants: Patients tested for COVID-19 from 3/3/2020-4/10/2020. Vi…

  • Global Cancer Surgery: pragmatic solutions to improve cancer surgery outcomes worldwide

    The Lancet Oncology · 2023-11-02 · 84 citations

    reviewOpen access
  • Association between vitamin D supplementation and COVID-19 infection and mortality

    Scientific Reports · 2022 · 71 citations

    HR = 0.75, [95% CI 0.55, 1.04]). We also find that after controlling for vitamin D blood levels, veterans receiving higher dosages of Vitamin D obtained greater benefits from supplementation than veterans receiving lower dosages. Veterans with Vitamin D blood levels between 0 and 19 ng/ml exhibited the largest decrease in COVID-19 infection following supplementation. Black veterans received greater associated COVID-19 risk reductions with supplementation than White veterans. As a safe, widely av…

Recent grants

Frequent coauthors

  • Vineet M. Arora

    126 shared
  • Marshall H. Chin

    University of Chicago

    50 shared
  • James Zhang

    Boston Scientific (United States)

    30 shared
  • Elbert S. Huang

    University of Chicago

    30 shared
  • Anirban Basu

    University of Washington

    28 shared
  • Margaret A. McLaughlin

    Lehigh University

    25 shared
  • Daniel P. Dunham

    25 shared
  • Urmimala Sarkar

    University of California, San Francisco

    25 shared

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