Christopher Brace
· ProfessorUniversity of Wisconsin-Madison · Radiology
Active 1993–2026
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About
Dr. Christopher Brace is a professor with the Departments of Radiology and Biomedical Engineering at the University of Wisconsin–Madison. He received his bachelor of science degrees in physics and electrical engineering from the University of Wisconsin–Milwaukee in 2001, followed by a master of science in electrical engineering and a doctor of philosophy from the University of Wisconsin–Madison in 2003 and 2005, respectively. Dr. Brace has been a member of the University of Wisconsin faculty since 2009, after serving as an Assistant Scientist from 2005 to 2009. His research interests include applications of electromagnetics in medicine, image-guided interventional oncology, thermal therapies such as radiofrequency and microwave ablation, multiphysics simulation, and medical imaging. He is the author of numerous papers, conference presentations, book chapters, and patents, with much of his work funded by federal and institutional grants.
Research topics
- Medicine
- Materials science
- Internal medicine
- Biomedical engineering
- Medical physics
- Physics
- Optics
- Optoelectronics
- Nuclear medicine
- Statistics
Selected publications
Heating technology for malignant tumors: a review
International Journal of Hyperthermia · 2020 · 386 citations
The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia, i.e., heating to 39-45 °C to induce sensitization to radiotherapy and chemotherapy, and thermal ablation, where temperatures beyond 50 °C destroy tumor cells directly are frequently applied in the clinic. Achievement of an effective treatment requires high quality heating equipment, precise thermal dosimetry, and adequate quality assurance. Several types of devices, antennas and heating or power deliver…
Radiology · 2021 · 165 citations
See also the editorial by Liddell in this issue.
International Journal of Hyperthermia · 2020 · 25 citations
Low power ablations, even if controlled for total energy delivery, create small ablation zones. High peak powers are associated with larger ablation zones and high margin temperatures if cooling pauses are avoided. Ramping and pulsing protocols with interleaved cooling appear to be of no benefit versus continuous 65 W for creating large ablation zones.
An Analysis of Open-Ended Coaxial Probe Sensitivity to Heterogeneous Media
Sensors · 2020-09-19 · 20 citations
articleOpen access1st authorCorrespondingOpen-ended coaxial probe spectroscopy is commonly used to determine the dielectric permittivity of biological tissues. However, heterogeneities in the probe sensing region can limit measurement precision and reproducibility. This study presents an analysis of the coaxial probe sensing region to elucidate the effects of heterogeneities on measured permittivity. Coaxial probe spectroscopy at 0.5-20 GHz was numerically simulated while a homogenous background was perturbed with a small inclusion of…
Medical Physics · 2020-11-25 · 14 citations
articleOpen accessSenior authorCorrespondingPurpose Intra‐procedural monitoring and post‐procedural follow‐up is necessary for a successful ablation treatment. An imaging technique which can assess the ablation geometry accurately is beneficial to monitor and evaluate treatment. In this study, we developed an automated ablation segmentation technique for serial low‐dose, noisy ablation computed tomography (CT) or contrast‐enhanced CT (CECT). Methods Low‐dose, noisy temporal CT and CECT volumes were acquired during microwave ablation on no…
Recent grants
NIH · $293k · 2013
NIH · $1.2M · 2016
NIH · $941k · 2014
Frequent coauthors
- 108 shared
Fred T. Lee
University of Wisconsin–Madison
- 86 shared
J. Louis Hinshaw
University of Wisconsin–Madison
- 64 shared
Meghan G. Lubner
University of Wisconsin–Madison
- 47 shared
Timothy J. Ziemlewicz
University of Wisconsin–Madison
- 47 shared
Lisa A. Sampson
University of Wisconsin–Madison
- 43 shared
Paul F. Laeseke
University of Wisconsin–Madison
- 34 shared
Shane A. Wells
- 14 shared
Tina M. Frey
University of Wisconsin–Madison
Education
- 2001
B.S., Physics
University of Wisconsin–Milwaukee
- 2001
B.S., Electrical Engineering
University of Wisconsin–Milwaukee
M.S., Electrical Engineering
University of Wisconsin–Milwaukee
Ph.D., Electrical Engineering
University of Wisconsin–Milwaukee
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