Charles R Horsburgh
· Professor, Global Health - Boston University School of Public HealthBoston University · Global Health
Active 1981–2025
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About
Charles R Horsburgh is a professor at Boston University School of Public Health, with faculty positions in the Departments of Epidemiology, Biostatistics, Global Health, and Medicine. He has 30 years of experience in public health and medicine. His research focuses on tuberculosis, nontuberculous mycobacterial infections, and opportunistic infections in AIDS. Dr. Horsburgh teaches courses in the Epidemiology of AIDS, the Epidemiology of Tuberculosis, and Vaccine Epidemiology. He is involved in research across multiple countries including Brazil, India, South Africa, Tanzania, Vietnam, and the Philippines. Additionally, he serves on the Board of Directors of the International Union Against Tuberculosis and Lung Disease (IUATLD) and is the Chairman of the Steering Committee of RESIST-TB, an organization dedicated to improving MDR-TB treatment through clinical trials and dissemination of best practices.
Research topics
- Pathology
- Medicine
- Internal medicine
- Environmental health
- Immunology
- Virology
- Psychology
- Pediatrics
- Economic growth
- Intensive care medicine
Selected publications
MMWR Recommendations and Reports · 2020 · 478 citations
Comprehensive guidelines for treatment of latent tuberculosis infection (LTBI) among persons living in the United States were last published in 2000 (American Thoracic Society. CDC targeted tuberculin testing and treatment of latent tuberculosis infection. Am J Respir Crit Care Med 2000;161:S221-47). Since then, several new regimens have been evaluated in clinical trials. To update previous guidelines, the National Tuberculosis Controllers Association (NTCA) and CDC convened a committee to condu…
The Lancet · 2020 · 343 citations
The impact of alcohol use on tuberculosis treatment outcomes: a systematic review and meta-analysis
The International Journal of Tuberculosis and Lung Disease · 2020 · 118 citations
Alcohol use is associated with increased risk of developing tuberculosis (TB) disease, yet the impact of alcohol use on TB treatment outcomes has not been summarized. We aimed to quantitatively review evidence of the relationship between alcohol use and poor TB treatment outcomes. We conducted a systematic review of PubMed, EMBASE, and Web of Science (January 1980-May 2018). We categorized studies as having a high- or low-quality alcohol use definition and examined poor treatment outcomes indivi…
Clinical Infectious Diseases · 2021 · 38 citations
BACKGROUND: Undernutrition is the leading cause of tuberculosis (TB) in India and is associated with increased TB mortality. Undernutrition also decreases quality of life and economic productivity. METHODS: We assessed the cost-effectiveness of providing augmented rations to undernourished Indians through the government's Targeted Public Distribution System (TPDS). We used Markov state transition models to simulate disease progression and mortality among undernourished individuals in 3 groups: g…
Impact of US Government funding cessation on TB care and prevention: a multicountry survey in Africa
The International Journal of Tuberculosis and Lung Disease · 2025-04-25 · 7 citations
article
Recent grants
BU Clinical HIV/AIDS Research Training Program (BU-CHART
NIH · $5.5M · 2003–2026
Phase 2 Pharmacodynamic Study of High-dose Levofloxacin in MDR-TB Treatment
NIH · $5.4M · 2013–2020
Predictors of Resistance Emergence Evaluation in MDR-TB Patients on Treatment (PREEMPT)
NIH · $4.6M · 2017–2024
Frequent coauthors
- 122 shared
Keertan Dheda
- 113 shared
Nesri Padayatchi
Centre for the AIDS Programme of Research in South Africa
- 106 shared
Lise Werner
Centre for the AIDS Programme of Research in South Africa
- 105 shared
Max R. O’Donnell
Columbia University Irving Medical Center
- 101 shared
Christoph Lange
University of Lübeck
- 97 shared
Charlotte Kvasnovsky
University of Chicago
- 92 shared
Iqbal Master
R. K. Khan Hospital
- 86 shared
Jennifer Zelnick
Touro College
Labs
Awards & honors
- Horsburgh Honored With Lifetime Achievement Award (2014)
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