Cameron Currie

About

Cameron Currie is a professor in the Department of Bacteriology at the University of Wisconsin-Madison and is an affiliate faculty member in the Department of Entomology. His research interests include the evolutionary ecology of the attine ant-microbe quadripartite symbiosis. He is based in the Microbial Sciences Building at 5207, 1550 Linden Drive, Madison, WI 53706. His contact information includes a phone number, 608-265-8034, and an email address, currie@bact.wisc.edu. The Currie Lab website provides further insights into his research focus, which centers on the complex interactions between ants and their associated microbes, emphasizing the evolutionary and ecological aspects of these symbiotic relationships.

Research topics

• Biology
• Genetics
• Computational biology
• Computer Science
• Evolutionary biology
• Ecology
• Biochemistry
• Astronomy
• Bioinformatics
• Botany

Selected publications

• A genomic catalog of Earth’s microbiomes

  Nature Biotechnology · 2020 · 963 citations

  The reconstruction of bacterial and archaeal genomes from shotgun metagenomes has enabled insights into the ecology and evolution of environmental and host-associated microbiomes. Here we applied this approach to >10,000 metagenomes collected from diverse habitats covering all of Earth's continents and oceans, including metagenomes from human and animal hosts, engineered environments, and natural and agricultural soils, to capture extant microbial, metabolic and functional potential. This compre…

  PublisherOA PDFDOI

• Unraveling the functional dark matter through global metagenomics

  Nature · 2023 · 193 citations

  . Using massively parallel graph-based clustering, we group these proteins into 106,198 novel sequence clusters with more than 100 members, doubling the number of protein families obtained from the reference genomes clustered using the same approach. We annotate these families on the basis of their taxonomic, habitat, geographical and gene neighbourhood distributions and, where sufficient sequence diversity is available, predict protein three-dimensional models, revealing novel structures. Overa…

  PublisherOA PDFDOI

• A marine microbiome antifungal targets urgent-threat drug-resistant fungi

  Science · 2020 · 172 citations

  Leveraging the microbiomes of marine animals and cutting-edge metabolomics and genomic tools, we identified encouraging lead antifungal molecules with in vivo efficacy. The most promising lead, turbinmicin, displays potent in vitro and mouse-model efficacy toward multiple-drug-resistant fungal pathogens, exhibits a wide safety index, and functions through a fungal-specific mode of action, targeting Sec14 of the vesicular trafficking pathway. The efficacy, safety, and mode of action distinct from…

  DOI

• A community resource for paired genomic and metabolomic data mining

  Nature Chemical Biology · 2021 · 129 citations

  biosynthetic origins and metabolite structures.

  DOI

• Fungal impacts on Earth’s ecosystems

  Nature · 2025-02-05 · 79 citations

  reviewOpen access
  PublisherOA PDFDOI

Recent grants

• NIH Grant RC4GM096347

  NIH · $2.5M · 2013

• Mode of Action Core

  NIH · $61.7M · 2019–2025

• NIH Grant U19AI109673

  NIH · $32.5M · 2019

Frequent coauthors

• Garret Suen

  University of Wisconsin–Madison

  92 shared

• Michael Poulsen

  University of Copenhagen

  91 shared

• Jon Clardy

  Harvard University

  85 shared

• Jarrod J. Scott

  Smithsonian Tropical Research Institute

  79 shared

• Frank O. Aylward

  Virginia Tech

  64 shared

• Bradon R. McDonald

  45 shared

• Marc G. Chevrette

  Florida Museum of Natural History

  44 shared

• Lynne Goodwin

  Los Alamos National Laboratory

  44 shared

Education

• Ph.D., Entomology

  University of California, Berkeley

  2000

• M.S., Entomology

  University of California, Berkeley

  1996

• B.S., Entomology

  University of California, Davis

  1994

Similar researchers at University of Wisconsin-Madison

• Anthony Ivesh-88
• Claudio Grattonh-61
• Bobbi Peckarskyh-53