Amitha Domalpally
· Associate ProfessorUniversity of Wisconsin-Madison · Ophthalmology and Visual Sciences
Active 2008–2026
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About
Amitha Domalpally, MD, PhD, is an Assistant Professor and the Scientific Director at the A-EYE Research Unit at the University of Wisconsin–Madison. Her role involves leading research efforts in the field of artificial intelligence for eye-related applications. She is part of a team that focuses on advancing AI technologies to improve eye health and ophthalmology.
Research topics
- Medicine
- Ophthalmology
- Internal medicine
- Optometry
- Surgery
- Pediatrics
- Endocrinology
- Psychology
Selected publications
JAMA Network Open · 2021 · 219 citations
Importance: Diabetic retinopathy (DR) is a leading cause of blindness in adults worldwide. Early detection and intervention can prevent blindness; however, many patients do not receive their recommended annual diabetic eye examinations, primarily owing to limited access. Objective: To evaluate the safety and accuracy of an artificial intelligence (AI) system (the EyeArt Automated DR Detection System, version 2.1.0) in detecting both more-than-mild diabetic retinopathy (mtmDR) and vision-threaten…
JAMA Ophthalmology · 2022 · 165 citations
Importance: After the Age-Related Eye Disease Study 2 (AREDS2) study, the beta carotene component was replaced by lutein/zeaxanthin for the development of the revised AREDS supplement. However, it is unknown if the increased risk of lung cancer observed in those assigned beta carotene persists beyond the conclusion of the AREDS2 trial and if there is a benefit of adding lutein/zeaxanthin to the original AREDS supplement that can be observed with long-term follow-up. Objective: To assess 10-year…
Artificial Intelligence Detection of Diabetic Retinopathy
Ophthalmology Science · 2022 · 135 citations
Objective: To compare general ophthalmologists, retina specialists, and the EyeArt Artificial Intelligence (AI) system to the clinical reference standard for detecting more than mild diabetic retinopathy (mtmDR). Design: Prospective, pivotal, multicenter trial conducted from April 2017 to May 2018. Participants: Participants were aged ≥ 18 years who had diabetes mellitus and underwent dilated ophthalmoscopy. A total of 521 of 893 participants met these criteria and completed the study protocol.…
Diabetes Care · 2021 · 98 citations
OBJECTIVE: To determine whether metformin or lifestyle modification can lower rates of all-cause and cause-specific mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study. RESEARCH DESIGN AND METHODS: From 1996 to 1999, 3,234 adults at high risk for type 2 diabetes were randomized to an intensive lifestyle intervention, masked metformin, or placebo. Placebo and lifestyle interventions stopped in 2001, and a modified lifestyle program was offered to everyone,…
Retinal Specialist versus Artificial Intelligence Detection of Retinal Fluid from OCT
Ophthalmology · 2020 · 92 citations
Frequent coauthors
- 162 shared
Emily Y. Chew
National Eye Institute
- 111 shared
Ronald P. Danis
- 91 shared
Elvira Agrón
National Eye Institute
- 73 shared
Barbara A. Blodi
University of Wisconsin–Madison
- 71 shared
Tiarnán D L Keenan
National Eye Institute
- 68 shared
Traci E. Clemons
Eunice Kennedy Shriver National Institute of Child Health and Human Development
- 60 shared
Barbara Blodi
- 57 shared
Jeong W. Pak
University of Wisconsin–Madison
Labs
Education
- 2003
M.D., Ophthalmology
University of Wisconsin-Madison
- 1999
B.S., Biology
University of Wisconsin-Madison
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