Denise Roe
VerifiedUniversity of Arizona · Pharmacology and Toxicology
Active 1982–2024
Research topics
- Internal medicine
- Medicine
- Clinical psychology
- Pathology
- Developmental psychology
- Physical therapy
- Biology
- Psychology
- Oncology
Selected publications
Breast Cancer Research and Treatment · 2022 · 6 citations
- Medicine
- Physical therapy
- Internal medicine
Clinical Epigenetics · 2022 · 24 citations
- Medicine
- Pathology
- Oncology
We tested the ability of a novel DNA methylation biomarker set to distinguish metastatic pancreatic cancer cases from benign pancreatic cyst patients and to monitor tumor dynamics using quantitative DNA methylation analysis of cell-free DNA (cfDNA) from blood samples. The biomarkers were able to distinguish malignant cases from benign disease with high sensitivity and specificity (AUC = 0.999). Furthermore, the biomarkers detected a consistent decline in tumor-derived cfDNA in samples from patients undergoing chemotherapy. The study indicates that our liquid biopsy assay could be useful for management of pancreatic cancer patients.
Ethical Human Psychology and Psychiatry · 2020 · 4 citations
Senior authorCorresponding- Psychology
- Developmental psychology
- Clinical psychology
Recent grants
NIH · $66.0M · 2017
NIH · $31.9M · 1997–2027
NIH · $72.6M · 2011
NIH · $40.7M · 2013
Frequent coauthors
- 147 shared
Patricia A. Thompson
- 129 shared
David S. Alberts
University of Arizona
- 111 shared
Peter Lance
University of Arizona
- 97 shared
Elizabeth T. Jacobs
University of Arizona
- 96 shared
H.‐H. Sherry Chow
University of Arizona Cancer Center
- 87 shared
Haiyan Cui
- 76 shared
Pavani Chalasani
George Washington University
- 75 shared
Kathylynn Saboda
University of Arizona Cancer Center
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