About

Yvonne Y. Chan, M.D., is an Assistant Professor specializing in Pediatric Urology at UC Davis Health. She has a passion for caring for children with a broad range of urologic conditions and seeks to incorporate her interest in quality improvement into her clinical care to enhance patient outcomes. Her clinical interests include spina bifida, minimally invasive surgery, hypospadias, vesicoureteral reflux, and complex urologic construction. Dr. Chan believes that every child deserves the chance to be a kid and emphasizes clear communication and shared decision making with patients and their families to ensure they thoroughly understand their conditions and management options. She aims to support patients with congenital urologic conditions requiring lifelong medical attention, helping them understand their conditions and how to care for themselves as they approach early adulthood, while also providing medical or surgical interventions to improve their quality of life. Her research interests include patient safety and quality improvement, post-surgical outcomes, and medical education. She has implemented enhanced recovery protocols for children with spina bifida undergoing bladder reconstruction to improve their post-operative recoveries. Dr. Chan is active in simulation design and in improving urologic surgical education for residents, reflecting her commitment to advancing both clinical practice and training in pediatric urology.

Research topics

• Medicine
• Surgery
• Urology
• Biomedical engineering
• Developmental psychology
• General surgery
• Andrology
• Medical physics
• Psychology
• Biology
• Cell biology
• Operations management
• Pathology

Selected publications

• Ambulatory status and sexual function and activity in young adults with spina bifida

  Journal of Pediatric Urology · 2025-01-30 · 2 citations

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• Bladder outlet procedures without augmentation cystoplasty: Long-term outcomes and association of preoperative bladder compliance with subsequent augmentation cystoplasty or urinary diversion and DMSA abnormalities

  Journal of Pediatric Urology · 2025-03-01

  articleOpen access
  PublisherOA PDFDOI

• Leveraging NSQIPP testicular torsion process measures: Initial survey of the NSQIPP testicular torsion collaborative

  Journal of Pediatric Urology · 2025-06-25 · 3 citations

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  PublisherDOI

• Multipotent bone marrow cell–seeded polymeric composites drive long-term, definitive urinary bladder tissue regeneration

  PNAS Nexus · 2024-01-30 · 9 citations

  articleOpen access

  Abstract To date, there are no efficacious translational solutions for end-stage urinary bladder dysfunction. Current surgical strategies, including urinary diversion and bladder augmentation enterocystoplasty (BAE), utilize autologous intestinal segments (e.g. ileum) to increase bladder capacity to protect renal function. Considered the standard of care, BAE is fraught with numerous short- and long-term clinical complications. Previous clinical trials employing tissue engineering approaches for bladder tissue regeneration have also been unable to translate bench-top findings into clinical practice. Major obstacles still persist that need to be overcome in order to advance tissue-engineered products into the clinical arena. These include scaffold/bladder incongruencies, the acquisition and utility of appropriate cells for anatomic and physiologic tissue recapitulation, and the choice of an appropriate animal model for testing. In this study, we demonstrate that the elastomeric, bladder biomechanocompatible poly(1,8-octamethylene-citrate-co-octanol) (PRS; synthetic) scaffold coseeded with autologous bone marrow-derived mesenchymal stem cells and CD34+ hematopoietic stem/progenitor cells support robust long-term, functional bladder tissue regeneration within the context of a clinically relevant baboon bladder augmentation model simulating bladder trauma. Partially cystectomized baboons were independently augmented with either autologous ileum or stem-cell-seeded small-intestinal submucosa (SIS; a commercially available biological scaffold) or PRS grafts. Stem-cell synergism promoted functional trilayer bladder tissue regeneration, including whole-graft neurovascularization, in both cell-seeded grafts. However, PRS-augmented animals demonstrated fewer clinical complications and more advantageous tissue characterization metrics compared to ileum and SIS-augmented animals. Two-year study data demonstrate that PRS/stem-cell-seeded grafts drive bladder tissue regeneration and are a suitable alternative to BAE.

  PublisherOA PDFDOI

• Training the next generation of quality improvement champions in pediatric urology: A virtual program co-sponsored by the journal of pediatric urology

  Journal of Pediatric Urology · 2024-05-23

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  PublisherDOI

• Emergent robot-to-open conversion – Multidisciplinary simulation training in crisis management

  Journal of Pediatric Urology · 2024-06-15 · 6 citations

  review1st authorCorresponding
  PublisherDOI

• Response to correspondence regarding “Emergent robot-to-open conversion-multidisciplinary simulation training in crisis management”

  Journal of Pediatric Urology · 2024-07-16

  letter1st authorCorresponding
  PublisherDOI

• Clinical utility and interrater reliability of video urodynamics in children with isolated fibrolipoma of filum terminale

  Journal of Pediatric Urology · 2023-05-05 · 3 citations

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  PublisherDOI

• Feasibility of Enhanced Recovery After Surgery (ERAS) implementation in Pediatric Urology: Pilot-phase outcomes of a prospective, multi-center study

  Journal of Pediatric Urology · 2023-12-30 · 8 citations

  articleOpen access
  PublisherOA PDFDOI

• Ureteral stent extraction strings in children: Stratifying the risk of post operative urinary tract infection

  Journal of Pediatric Urology · 2023-06-02 · 5 citations

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  PublisherDOI

Frequent coauthors

• Eric A. Kurzrock

  31 shared

• David I. Chu

  Lurie Children's Hospital

  19 shared

• Arun K. Sharma

  15 shared

• Earl Y. Cheng

  Northwestern University

  15 shared

• Craig A. Peters

  Children's Medical Center

  14 shared

• Ilina Rosoklija

  Lurie Children's Hospital

  14 shared

• Elizabeth B. Yerkes

  14 shared

• Edward M. Gong

  Lurie Children's Hospital

  12 shared

Education

• Resident, Urology

  UC Davis Health System

  2018

• M.D.

  David Geffen School of Medicine at UCLA

  2012

• B.S., Biology

  Stanford University

  2008

Awards & honors

• Recipient of the Armstrong Endowment for Compassionate Care,…
• Provider of the Month Outpatient Clinics (2020)